2016
DOI: 10.1002/jhm.2662
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Preventing acute care–associated venous thromboembolism in adult and pediatric patients across a large healthcare system

Abstract: BACKGROUND Although effective methods for venous thromboembolism prophylaxis (VTE‐P) have been known for decades, reliable implementation has been challenging. OBJECTIVE Develop reliable VTE‐P systems for adult and for pediatric patients to reduce preventable venous thromboembolism (VTE). DESIGN We used a discovery and diffusion system to first develop an effective system in 1 hospital location, and then spread the principle best practices across the entire 22‐hospital system. SETTING Twenty‐two Mayo Clinic ho… Show more

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Cited by 9 publications
(7 citation statements)
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“…Slightly more standard care than BioFlo ® patients were free of such comorbidities (25% vs 16%), yet standard care patients still had the higher number of thromboses (7% vs 3%). Morgenthaler and Rodriguez 37 reported vascular access‐associated thrombosis in pediatrics to be less common than in adults but higher in medically complex children. Worryingly, Menendez et al 38 reported pediatric thrombosis to be largely asymptomatic, so the true incidence in our study is likely higher because only radiologically confirmed thromboses were recorded.…”
Section: Discussionmentioning
confidence: 99%
“…Slightly more standard care than BioFlo ® patients were free of such comorbidities (25% vs 16%), yet standard care patients still had the higher number of thromboses (7% vs 3%). Morgenthaler and Rodriguez 37 reported vascular access‐associated thrombosis in pediatrics to be less common than in adults but higher in medically complex children. Worryingly, Menendez et al 38 reported pediatric thrombosis to be largely asymptomatic, so the true incidence in our study is likely higher because only radiologically confirmed thromboses were recorded.…”
Section: Discussionmentioning
confidence: 99%
“…This may be because interventions were largely based around venous thromboembolism prophylaxis, which is not routinely used in pediatric patients younger than 12 years. However, prophylaxis strategies represent a value-added intervention that minimizes ADEs and high-risk complications in critically ill patients or at transitions of care if prophylactic agents are continued (35)(36)(37).…”
Section: What This Study Meansmentioning
confidence: 99%
“…Thrombosis and intraluminal occlusions are the most common cause of PICC failure in pediatric patients (Menendez et al 2016;Morgenthaler and Rodriguez 2016). A recent development in PICC material involves the incorporation of antithrombogenic material (Endexo™) throughout the catheter-the inside, the outside, and the cut surface.…”
Section: Catheter Materials and Designmentioning
confidence: 99%