Preventing premature deaths from breast and cervical cancer among underserved women in the United States: insights gained from a national cancer screening program

White, Mary C.; Wong, Faye L.

doi:10.1007/s10552-015-0541-4

Cited by 19 publications

(18 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Studies showed that many environmental factors consumption were the risk in population, and we found environmental risk factors, which were not consistent to previous reports (Chang et al 2014;L. D. Wang et al 2014;White & Wong, 2015). This might be interpreted by the fact that gene susceptibility was variable in different ethnics.…”

Section: Discussioncontrasting

confidence: 99%

Research Article Association between polymorphisms in TLR4 gene targeted by microRNA-140 and cervical precancerous lesion in south Chinese women: a case control study

Huang¹,

Li²,

Zhong³

et al. 2017

Genet. Mol. Res.

View full text Add to dashboard Cite

Toll-like receptor 4 (TLR4), one of the key immune system effectors, plays a main role in immune recognition of cervical cancer. Micro-RNAs are involved in regulation of multiple important genes in the progression of cervical cancer. A case-control study of 592 people was conducted from Yun'an County, Yunfu City, Guangdong Province, China. Cervical fall off epithelia were collected to detect human papilloma virus (HPV), followed by Thin Prep cytology test (TCT). Moreover, extraction of DNA from peripheral blood were performed for genotyping from the 296 patients and another 296 age-matched healthy control subjects.

show abstract

Section: Discussioncontrasting

confidence: 99%

Research Article Association between polymorphisms in TLR4 gene targeted by microRNA-140 and cervical precancerous lesion in south Chinese women: a case control study

Huang¹,

Li²,

Zhong³

et al. 2017

Genet. Mol. Res.

View full text Add to dashboard Cite

show abstract

“…Cervical cancer screening programs have led to a sustained decline in cervical cancer incidence and mortality in developed countries and prevented premature deaths in underserved populations [3, 4]. This is attributable in part to early detection of invasive cervical cancer, thereby improving survival following treatment [5].…”

Section: Introductionmentioning

confidence: 99%

Cervical cancer survival in a resource-limited setting-North Central Nigeria

Musa

Nankat

Achenbach

et al. 2016

Infect Agents Cancer

View full text Add to dashboard Cite

BackgroundOrganized cervical cancer screening services are presently lacking in Nigeria contributing to late presentation and diagnosis of invasive cervical cancer cases (ICCs) at advanced stages in most gynecologic units in Nigeria. We evaluated outcomes of ICCs diagnosed at Jos University Teaching Hospital (JUTH) to better understand factors associated with cervical cancer survival in similar resource limited settings.MethodsWe performed a retrospective cohort study with a prospective follow up data to estimate time from diagnosis to mortality among women diagnosed with ICCs at JUTH. Women who were diagnosed with ICCs between January 2011 and May 2013 were followed up after initial evaluation at JUTH and subsequent referral for specialized treatment in one of the national oncology treatment centers in Nigeria. The main outcome measured was all-cause mortality rate and overall survival (OS) after diagnosis of ICC. The follow up data were updated and observations were censored March 31, 2015. The overall death rate was estimated using the total number of death events and the cumulative follow-up time from diagnosis to death. We conducted Cox proportional hazard regression to assess factors associated with death.ResultsA total of 65 histologically confirmed ICCs were followed up. The median age of the cohort was 50 years with a median parity of 7. The HIV prevalence in the cohort was 8.2 % and the majority (72.3 %) were diagnosed at advanced stages (AD) of ICC. Simple total abdominal hysterectomy (TAH) was performed in 38.9 % of patients who were diagnosed at early stage disease (ED). After a cumulative follow up of 526.17 months, 35 deaths occurred with an overall death rate of 79.8 per 100 women-years. We also found a significantly higher hazard of death in women with AD (HR = 3.3) and baseline anemia (HR = 3.0). In the subgroup of women with ED, the OS was significantly higher for those who had TAH compared to those who did not (26.5 versus 11.6 months respectively).ConclusionAdvanced stage disease and baseline anemia were independently associated with higher death rate. Cervical cancer patients diagnosed at early stages by non-oncologic specialist in settings lacking the standard of care may benefit from improve survival with simple hysterectomy.

show abstract

“…The final article highlights these valuable insights and discusses future opportunities for the NBCCEDP [17]. As the only nationally organized cancer screening program in the USA, the NBCCEDP provides a model to guide future efforts in improving the provision of preventive health services and understanding the impact of these services on reducing breast and cervical cancer mortality among all women in the USA.…”

mentioning

confidence: 99%

The Reach and Health Impacts of the National Breast and Cervical Cancer Early Detection Program

Guy

Tangka

Hall

et al. 2015

Cancer Causes Control

View full text Add to dashboard Cite

Preventing premature deaths from breast and cervical cancer among underserved women in the United States: insights gained from a national cancer screening program

Cited by 19 publications

References 33 publications

Research Article Association between polymorphisms in TLR4 gene targeted by microRNA-140 and cervical precancerous lesion in south Chinese women: a case control study

Research Article Association between polymorphisms in TLR4 gene targeted by microRNA-140 and cervical precancerous lesion in south Chinese women: a case control study

Cervical cancer survival in a resource-limited setting-North Central Nigeria

The Reach and Health Impacts of the National Breast and Cervical Cancer Early Detection Program

Contact Info

Product

Resources

About