“…Some studies have recommended incorporation of hand hygiene into the ventilator bundle (Bouadma, Mourvillier, Deiler, Le Corre, et al, 2010;Tolentino-DelosReyes, Ruppert, & Shiao, 2007). In paediatric and neonatal settings, hand hygiene becomes instrumental in the prevention of infection (Azab et al, 2015;Obeid et al, 2014), as children's immature host defence makes them more susceptible to infection compared to adults (Chhapola & Brar, 2015). For instance, two paediatric pre-post implementation study designs incorporating hand hygiene into their ventilator bundle by Bigham et al, (2009) and multicentred study by Rosenthal, Alvarez-Moreno, et al (2012) In PICU, hand hygiene is identified as a key target for quality improvement efforts (Harris et al, 2011).…”