Prevention and risk assessment of cardiovascular events in a population of patients with psoriasis and psoriatic arthritis

Abstract

Psoriasis is a chronic, inflammatory, often relapsing disease that is frequently associated with other diseases of similar pathogenesis. The multi-morbidity in the psoriasis population significantly impedes both diagnosis and implementation of appropriate preventive measures. However, the common denominator for this group of diseases is the inflammatory process that initiates the appearance of subsequent symptoms and health consequences, most of which can be avoided or alleviated by modifying the patient's lifestyle and incorporating appropriate treatment. Health consequences associated with systemic inflammation include cardiovascular incidents and other cardiometabolic diseases. This article was based on available publications on the onset, incidence, and prevention of cardiovascular disease in the psoriasis patient population.

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension

“…BBs may trigger or worsen psoriasis and should be avoided if possible or carefully used in the presence of compelling indications [1545] (Table 16). Glucose control should be considered in patients with hypertension and psoriatic arthritis [1546].…”

Causes of Autoimmune Psoriasis and Associated Cardiovascular Disease: Roles of Human Endogenous Retroviruses and Antihypertensive Drugs—A Systematic Review and Meta-analysis

“…In addition, the role of microRNAs, as well-known small, single-stranded, noncoding RNA molecules with a crucial role in gene expression, in psoriasis-induced CVD has also been explored 43 . For example, the expression of miR-200c is increased in PsD patients, reflecting endothelial dysfunction.…”