2019
DOI: 10.1007/164_2019_341
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Prevention and Treatment of Atherosclerosis: The Use of Nutraceuticals and Functional Foods

Abstract: Nutritional interventions are effective and – in theory – easy to implement primary and secondary prevention strategies that reduce several risk factors of atherosclerosis and cardiovascular disease (CVD). Yet, because of (a) the severe impact of CVD in terms of mortality, morbidity, quality of life, and economy, (b) the proved role of LDL plasma concentrations as the most critical risk factor, and (c) the obstacles found both in terms of biological effects and compliance of the patient by an exclusively dieta… Show more

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Cited by 7 publications
(10 citation statements)
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“…plant sterols and stanols (collectively known as phytosterols), monacolin K (as an ingredient of red yeast rice), berberine, beta-glucans, and other fibers. Our critical insight adds to other recent publications on this subject (16)(17)(18).…”
Section: Most Active Functional Foods and Supplements Used To Lower Plasma Ldl-c Concentrationssupporting
confidence: 65%
“…plant sterols and stanols (collectively known as phytosterols), monacolin K (as an ingredient of red yeast rice), berberine, beta-glucans, and other fibers. Our critical insight adds to other recent publications on this subject (16)(17)(18).…”
Section: Most Active Functional Foods and Supplements Used To Lower Plasma Ldl-c Concentrationssupporting
confidence: 65%
“…Epidemiological and clinical studies indicate that the risk of CVD is reduced by a diet rich in fruits, vegetables, unrefined grains, fish and low-fat dairy products, and low in saturated fats and sodium. Although adherence could be difficult, nutritional interventions are effective primary prevention strategies to reduce several risk factors of CVD including LDL-C concentrations [70]. Whole diet approaches, such as the Portfolio diet successfully lowered TC and LDL-C concentrations [71].…”
Section: Functional Food Ingredients and Supplements In Universal/selective Preventionmentioning
confidence: 99%
“…Ayrıca, prebiyotik etkisi de göz önüne alınarak, emiliminden sonra kısa zincirli yağ asidi (SCFA) sentezinin artmasına yol açtığı belirlenmiştir. Karaciğerde kolesterol sentezinin inhibitörü olarak rol alır, yüksek dozajdaki beta glukan, öğün sonrası glisemik yanıtı da iyileştirebilmektedir (Visioli & Poli , 2019). Yulaf verilmesinin ardından barsaklarda artan viskozitenin; glikoz, kolesterol ve safra asitlerinin geri emilimini inhibe etmesi ile, diyabet ve kalp damar hastalıklarını oluşturan kan parametrelerinden; glikoz, insülin ve kolesterol düzeylerinin düşürüldüğü (β-glukan içeren viskoz ve çözünür diyet posaları ile) bilinmektedir (Vetvicka, 2019).…”
Section: Beta Glukanunclassified
“…Bu faktörlerden en başta gelenlerden birinin, düşük yoğunluklu lipoprotein (LDL) kolesteroldeki artış olduğu olduğu düşünülmektedir. Mendel'in randomizasyon deneyleri ve birçok müdahale çalışmaları, plazma LDL kolesterol seviyelerindeki artışların kardiyovasküler riskle ilişkili olduğunu göstermiştir (Visioli & Poli , 2019).…”
Section: Introductionunclassified
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