Prevention of allergic contact dermatitis with alternative products

Sertoli, A.; Francalanci, Simona; Giorgini, S.; Brusi, Claudio; Acciai, M. C.

doi:10.1111/j.1600-0536.1994.tb02029.x

Cited by 5 publications

(3 citation statements)

References 5 publications

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“…Rubia cordifolia is an important medicinal plant which is used for treatment of various ailments in Ayurvedic system of medicine (George, 1967;Pandey and Chunnekar, 1967;Sertoli et al, 1994;Adwankar et al, 1980;Singh et al, 1983;Tripathi et al, 1993;Pandey et al, 1994). Rubiadin, isolated from the roots of Rubia cordifolia was found to have potent antioxidant property (Tripathi et al, 1993), In addition, rubiadin also have been found to inhibit lipid peroxidation (Tripathi and Sharma, 1998) and the plant Rubia cordifolia have been reported for anti-inflammatory (Antarkar et al, 1983), immunomodulatory (Joharapurkar et al, 2003), anticonvulsant and anxiolytic (Kasture et al, 2000) and anti-tumor activities (Manohar et al, 1982).…”

Section: Introductionmentioning

confidence: 96%

Hepatoprotective effects of rubiadin, a major constituent of Rubia cordifolia Linn.

Rao

Pushpangadan

et al. 2006

Journal of Ethnopharmacology

186

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Section: Introductionmentioning

confidence: 96%

Hepatoprotective effects of rubiadin, a major constituent of Rubia cordifolia Linn.

Rao

Pushpangadan

et al. 2006

Journal of Ethnopharmacology

186

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“…The popularity of a more natural lifestyle, based also on the use of natural and sustainable goods, is increasing the use of natural dyes due to their positive properties, such as not aggravating dermatitis conditions (14), unlike synthetic dyes (15,16), and their natural antimicrobial activity (17,18). It is consequently important to learn more about the UV protection properties of a large number of natural dyes when combined with natural fibers, like flax, commonly used to make summer clothes, and hemp which, in the near future, could join linen.…”

Section: Introductionmentioning

confidence: 99%

Laboratory and Outdoor Assessment of UV Protection Offered by Flax and Hemp Fabrics Dyed with Natural Dyes

Grifoni¹,

Bacci

Zipoli

et al. 2009

Photochem & Photobiology

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The safest protection from UV radiation (UVR) exposure is offered by clothing and its protectiveness depends on fabric composition (natural, artificial or synthetic fibers), fabric parameters (porosity, weight and thickness) and dyeing (natural or synthetic dyes, dye concentration, UV absorbing properties, etc.). In this study the UV protection properties of two fabrics made of natural fibers (flax and hemp) dyed with some of the most common natural dyes were investigated. UVR transmittance of fabrics was measured by two methods: one based on the utilization of a spectrophotometer equipped with an integrating sphere (in vitro test), and the other based on outdoor measurements taken by a spectroradiometer. Transmittance measurements were used to calculate the ultraviolet protection factor (UPF). Experimental results revealed that natural dyes could confer good UV protection, depending mainly on their different UVR-absorbing properties, provided that the fabric construction already guaranteed good cover. An increase in cover factor caused by the dyeing process was also detected. Weld-dyed fabrics gave the highest protection level. The comparison between the two methods applied to measure fabric transmittance pointed out that the UPFs calculated by in vitro measurements were generally lower than those based on outdoor data, indicating an underestimation of the actual protection level of tested fabrics assessed by the in vitro test.

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“…It has long cylindrical and typically red colored roots (Adwankar et al, 1980). Rubia cordifolia is an important medicinal plant which is used for treatment of various ailments in Ayurvedic system of medicine (Adwankar et al, 1980;Sertoli et al, 1994;Sridevi, 2011). The major active component of Rubia cordifolia Linn are anthraquinones glycosides and include 1-hydroxy 2-methoxy anthraquinone, 1, 4-dihydroxy-2-methyl-5-methoxy anthraquinone, 1, 3-dimethoxy 2-carboxy anthraquinone and rubiadin (1,3-dihydroxy-2-methyl anthraquinone) (Dosseh et al, 1981).…”

Section: Introductionmentioning

confidence: 99%

Induction of Apoptosis by Methanolic Extract of Rubia Cordifolia Linn in HEp-2 Cell Line is Mediated by Reactive Oxygen Species

Shilpa

Sivaramakrishnan²,

Devaraj³

2012

Asian Pacific Journal of Cancer Prevention

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Rubia cordifolia Linn, which belongs to the Rubiaceae family, is a well-known herb used in Ayurvedic medicine. In the present study, we investigated the influence of a methanolic extract (RC) on the induction of apoptosis in HEp-2 (human laryngeal carcinoma) cell line, as evidenced by cytotoxicity, morphological changes and modification in the levels of pro-oxidants. Inhibition of cell proliferation and lactate dehydrogenase (LDH) release increased in a time and dose-dependent manner. Further, reduced glutathione (GSH), glutathione transferase (GST) and protein levels decreased and lipid peroxidation increased significantly on RC treatment in a dose dependent manner when compared to controls. Based on the results we determined the optimal dose as 30mg/ ml and the apoptotic effect of RC extract (30 mg/ml) on HEp-2 cells was confirmed by fluorescent microscopy and transmission electron microscopy (TEM) based on morphological and ultrastructural changes. RC extract suppressed the proliferation of HEp-2 oral cancer cells inducing apoptotic cell death in vitro. These results point to potential of RC extract as an agent for the treatment of laryngeal squamous cell carcinoma.

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Prevention of allergic contact dermatitis with alternative products

Cited by 5 publications

References 5 publications

Hepatoprotective effects of rubiadin, a major constituent of Rubia cordifolia Linn.

Hepatoprotective effects of rubiadin, a major constituent of Rubia cordifolia Linn.

Laboratory and Outdoor Assessment of UV Protection Offered by Flax and Hemp Fabrics Dyed with Natural Dyes

Induction of Apoptosis by Methanolic Extract of Rubia Cordifolia Linn in HEp-2 Cell Line is Mediated by Reactive Oxygen Species

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