Prevention of atrial fibrillation after cardiac valvular surgery by epicardial, biatrial synchronous pacing

Debrunner, Marianne; Naegeli, Barbara; Genoni, Michele; Turina, Marko; Bertel, Osmund

doi:10.1016/s1010-7940(03)00644-4

Cited by 18 publications

(16 citation statements)

References 24 publications

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“…19 The usefulness of nonpharmacological strategies, such as continuous overdrive atrial pacing through temporary epicardial electrodes, is currently under investigation. 20 Beneficial effects of SNP in cardiac surgery have been reported in many studies. Massoudy et al 21 reported that administration of SNP (as an NO donor) for just the first 20 minutes of reperfusion to patients undergoing CABG led to a reduction of the acute inflammatory response, especially a reduction in levels of interleukin-6 and interleukin-8.…”

Section: Discussionmentioning

confidence: 99%

“…NO production by SNP requires the presence of vascular tissue. 20 The aim of the present prospective, blinded, randomized study was to evaluate the usefulness of SNP in preventing AF in patients undergoing first elective CABG. Here, we present the results of a pilot study designed to evaluate the effectiveness of perioperative (during the rewarming period) SNP administration and discuss possible strategies by which SNP treatment can be beneficial to prevent postoperative AF.…”

Section: Editorial P 467 Clinical Perspective P 481mentioning

confidence: 99%

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Does Sodium Nitroprusside Decrease the Incidence of Atrial Fibrillation After Myocardial Revascularization?

Cavolli¹,

Kaya²,

Aslan³

et al. 2008

Circulation

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Background-Atrial fibrillation (AF) often occurs after coronary artery bypass grafting and can result in increased morbidity and mortality. In the present pilot study, our aim was to investigate whether sodium nitroprusside (SNP), as a nitric oxide donor, can reduce the frequency of post-coronary artery bypass grafting AF. Methods and Results-To investigate the effectiveness of SNP in the prophylaxis of AF, we conducted a prospective, randomized, placebo-controlled clinical study on 100 consecutive patients in whom we performed elective and initial CABG operations. A control group of 50 patients were treated with placebo (dextrose 5% in water), whereas the SNP group (nϭ50 patients) was treated with SNP (0.5 g · kg Ϫ1 · min Ϫ1 ) during the rewarming period. High-sensitivity C-reactive protein levels were measured before surgery and 5 days postoperatively. All patients were monitored postoperatively with telemetry. Baseline characteristics were similar in both treatment groups. AF occurred in 12% of the SNP group and 27% of the control group. The occurrence of AF was significantly lower in the SNP group (Pϭ0.005). The duration of AF in the SNP group was significantly shorter than that in the control group (5.33Ϯ1.86 and 7.55Ϯ1.94 hours, respectively; Pϭ0.023). C-reactive protein levels were higher postoperatively in the control group than in the SNP group (PϽ0.05). Postoperative AF significantly prolonged postoperative hospital stay (PϽ0.05). Conclusions-The

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Section: Discussionmentioning

confidence: 99%

Section: Editorial P 467 Clinical Perspective P 481mentioning

confidence: 99%

Does Sodium Nitroprusside Decrease the Incidence of Atrial Fibrillation After Myocardial Revascularization?

Cavolli¹,

Kaya²,

Aslan³

et al. 2008

Circulation

View full text Add to dashboard Cite

show abstract

“…[20][21][22][23] Recently, several reports have shown that multisite temporary atrial pacing via epicardial electrodes placed during surgery might be effective in preventing postoperative AF. [24][25][26][27][28][29][30][31][32] In a double-blind, randomized study, Daoud et al evaluated the effects of different pacing modes in 118 patients who had undergone open heart surgery. 28 In this study, patients were randomized to one of the following three groups: right atrial pacing with an inhibited mode at a rate of 45 beats/min; right atrial overdrive pacing with a triggered mode ≥ 10 beats greater than the patient's intrinsic (but not < 85 beats/min) rate; and biatrial overdrive pacing with a triggered mode ≥ 10 beats greater than the patient's intrinsic (but not < 85 beats/min) rate.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of triple-site triggered atrial pacing for prevention of atrial fibrillation after coronary artery bypass graft surgery

et al. 2005

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SummaryBackground: Recently, several temporary multisite pacing methods have been developed for prevention of postoperative atrial fibrillation (AF).Hypothesis: In this study, we evaluated the effect of triplesite temporary triggered pacing in the AAT mode on the development of AF in patients undergoing coronary artery bypass graft (CABG) at high risk for developing postoperative AF.Methods: A total of 70 patients undergoing CABG were randomly assigned either to pacing group (study group, n = 35 patients) or to no pacing group (control group, n = 35 patients). The external pacemaker was programmed to pace at the atrial triggered mode at a lower rate of 40 beats/min for 4 days.Results: Atrial fibrillation, defined as lasting > 30 s, occurred in 4 patients (11.4%) in the study group and in 16 patients (45.7%) in the control group (p = 0.003). Sustained AF, defined as AF lasting > 10 min, also was observed less frequently in the study group than in the control group (11.6 vs. 37.1%, p = 0.024). Triple-site triggered atrial pacing was observed to reduce the incidence of AF by 75% and the incidence of sustained AF by 69%.Conclusions: We believe that multiple-site temporary pacing in the triggered mode is an effective way of preventing postoperative AF. This technique may be used especially in patients at high risk of developing AF.

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“…La prophylaxie de la FA postopé ratoire par une stimulation synchrone bi-atriale a é té suggé ré e par quelques é tudes [9,10]. Toutefois, cette mé thode de pré vention n'a pas é té validé e, malgré qu'elle soit incluse dans les recommandations ACCP 2005.…”

Section: Synthè Se Des Donné Esunclassified

Entraînement électrosystolique épicardique temporaire post-chirurgie cardiaque : modalités pratiques

Lazarescu

Mertès

Longrois³

2013

Annales Françaises d'Anesthésie et de Réanimation

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Prevention of atrial fibrillation after cardiac valvular surgery by epicardial, biatrial synchronous pacing

Abstract: Temporary, biatrial synchronous pacing during the first 3 postoperative days is safe and has a significant rhythm-stabilizing effect in patients undergoing valvular cardiac surgery.

Cited by 18 publications

References 24 publications

Does Sodium Nitroprusside Decrease the Incidence of Atrial Fibrillation After Myocardial Revascularization?

Does Sodium Nitroprusside Decrease the Incidence of Atrial Fibrillation After Myocardial Revascularization?

Effectiveness of triple-site triggered atrial pacing for prevention of atrial fibrillation after coronary artery bypass graft surgery

Entraînement électrosystolique épicardique temporaire post-chirurgie cardiaque : modalités pratiques

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