Prevention of depression in patients with cancer: A systematic review and meta-analysis of randomized controlled trials

Zahid, Jawad Ahmad; Grummedal, Ole; Madsen, Michael Tvilling; Gögenur, Ismail

doi:10.1016/j.jpsychires.2019.10.009

Cited by 24 publications

(11 citation statements)

References 52 publications

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“…with cancer can be prevented and prophylactic treatment should be administered during oncological treatment [50]. The treatment of depression must be started at an early stage.…”

Section: Plos Onementioning

confidence: 99%

Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study

et al. 2022

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Background Depression is a major public health problem among cancer patients undergoing chemotherapy. It compromises patient outcomes, resulting in higher rates of mortality. Currently, there are little data on the prevalence of depression in Sub-Sharan countries. Therefore, the current study was done to assess the prevalence of depression among adult cancer patients and its associated factors in Ethiopia. Method An institutional based cross-sectional study was conducted among 420 adult cancer patients from 1st March to April 30, 2021. Systematic random sampling technique was used to recruit participants. Depression was assessed using the Patient Health Questionnaire-9. The collected data were coded and entered into Epi-data version 4.2 and exported to SPSS version 25 for analysis. Bivariate binary logistic regression was performed to select factors that will be included in multivariate analysis, and variables with a p-value < 0.05 were included in multivariate analysis. In multivariate analysis, odds ratios and their 95% confidence intervals were computed and variables with p-value < 0.05 were considered to declare a significant association. Results In this study, the prevalence of depression was 33.1% (95% CI = 0.2858, 0.3761). Minimal symptoms of depression, minor depression, moderate depression, moderate severe depression, and severe depression were found to be 272 (64.8%), 9 (2.1%), 104 (24.8%), 28 (6.7%), and 7 (1.7%), respectively. Those cancer patients who had unemployed status, sacked from jobs, and had stage IV cancer were most likely to develop depression, whereas patients who completed primary education, colon, prostate and cervical cancer were less likely to have depression. Conclusion Depression is found to be a major public health concern for adult cancer patients in Ethiopia. To reduce the occurrence of depression among cancer patients, special attention is needed.

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“…with cancer can be prevented and prophylactic treatment should be administered during oncological treatment [50]. The treatment of depression must be started at an early stage.…”

Section: Plos Onementioning

confidence: 99%

Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study

et al. 2022

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“…According to our umbrella review, psychopharmacological treatments may be considered in individuals with subthreshold symptoms (indicated interventions) and individuals with medical conditions (Table 3). Antidepressants have been used as preventive treatments for individuals with hepatitis C treated by interferon-alpha (Ehret and Sobieraj, 2014;Jiang et al, 2014), and for individuals with cancer (Zahid et al, 2020) (see Table 3). Furthermore, antidepressants reduced the incidence of depression (RR=0.33) (Gu et al, 2020)-particularly those with a treatment duration ≥1 year (RR=0.34) (Salter et al, 2013)-and improved symptoms of depression (SMD=0.20) (Gu et al, 2020) after an acute stroke.…”

Section: Discussionmentioning

confidence: 99%

Primary prevention of depression: An umbrella review of controlled interventions

Pablo

Solmi

Vaquerizo‐Serrano

et al. 2021

Journal of Affective Disorders

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“…Studies have also shown that anxiety can be precipitated by concerns regarding physical function and maintaining social roles ( 80 ) as well as the financial toxicity of treatment ( 81 ), which may be prolonged in long-course adjuvant treatment and could be targets for prehabilitation. There has been little research on psychological prehabilitation prior to adjuvant treatment; however, a recent systematic review and meta-analysis of randomized controlled trials found that “prophylactic” pharmacotherapy, psychotherapy, and other interventions, including exercise, prevented or mitigated depression for those undergoing cancer treatment ( 82 ).…”

Section: Prehabilitation Prior To Adjuvant Treatmentmentioning

confidence: 99%

Multiphasic Prehabilitation Across the Cancer Continuum: A Narrative Review and Conceptual Framework

et al. 2021

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The field of cancer survivorship has significantly advanced person-centered care throughout the cancer continuum. Within cancer survivorship, the last decade has seen remarkable growth in the investigation of prehabilitation comprising pre-treatment interventions to prevent or attenuate the burden of oncologic therapies. While the majority of evidence remains in the surgical setting, prehabilitation is being adapted to target modifiable risk factors that predict poor treatment outcomes in patients receiving other systemic and localized anti-tumor treatments. Here, we propose a multiphasic approach for prehabilitation across the cancer continuum, as a conceptual framework, to encompass the variability in cancer treatment experiences while adopting the most inclusive definition of the cancer survivor.

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Prevention of depression in patients with cancer: A systematic review and meta-analysis of randomized controlled trials

Cited by 24 publications

References 52 publications

Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study

Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study

Primary prevention of depression: An umbrella review of controlled interventions

Multiphasic Prehabilitation Across the Cancer Continuum: A Narrative Review and Conceptual Framework

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