Prevention of fat embolism by early internal fixation of fractures in patients with multiple injuries

Intramedullary nailing of multiple long-bone fractures of the lower extremity at the same surgery: a single-center experience

“…Current recommendations for treating long-bone fractures in patients with multiple trauma are to proceed with early skeletal fixation (Ͻ48 hours after injury), provided adequate resuscitation has been obtained. 4,5,6,10,32,34 To our knowledge, there have been no studies focusing on patients who required multiple intramedullary nailing at the same operation. Excellent results have been reported on the use of intramedullary nails for treating lower limb fractures.…”

Non-Thrombotic Pulmonary Embolism

“…Early stabilization of the fractures as well as early operative intervention reduces the incidence and severity of FES (Al-Khuwaitir et al, 2002;A. B. Baker, 1976;Bone et al, 1989;Jenkins et al, 2002;Johnson & Lucas, 1996;Parisi et al, 2002;Riska et al, 1976;Riska & Myllynen, 1982;Svenningsen et al, 1987;Tachakra et al, 1990;Talucci et al, 1983). Early ( < 24 hours) fixation of the fracture of the femur was associated with an improved outcome even in patients with concomitant head and chest trauma (Brundage et al, 2002).…”

Current Concepts of Respiratory Insufficiency Syndromes After Fracture

“…There is, however, evidence that the use of nailing may actually be protective against FES in this situation. 42,83 Patients with pathological fractures treated by nailing and patients with fractures of the hip treated by cemented hemiarthroplasty are at a higher risk of developing a fulminant form of acute FES, either as a result of florid intraoperative FE, or from a pre-existing coagulopathic state.…”