Prevention of Gestational Diabetes

Callaway, Leonie K.; Colditz, Paul B.; Byrne, Nuala M.; Lingwood, Barbara E.; Rowlands, Ingrid J.; Foxcroft, Katie; McIntyre, H. David

doi:10.2337/dc09-2336

Cited by 127 publications

(191 citation statements)

References 13 publications

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“…These results are probably the most Iranian pregnant women receive average and inadequate pregnancy period cares (49), and some factors that are barriers for receiving the cares are the lack of need for the cares by women, and their lack of knowledge of the numbers and how to refer to health centers properly (50). Regression analysis showed among the pregnant women's characteristics, number of previous delivery only factor influencing women's preferences.…”

Section: Discussionmentioning

confidence: 94%

Prioritizing Pregnant Women’s Preferences to Receive Health Information Before and During Pregnancy in Semnan in 2014 - 2015

Kahouei

Niaki

Homayoon

et al. 2016

Middle East J Rehabil Health Stud

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Background: Given that family health is tied to women health, illness, or death of a woman has an adverse effect on the health of her child, family, and community; awareness of women's preferences in receiving health information can help to improve and modify the methods of informing and providing appropriate services to them, and also makes pregnant women training more efficient and more effective. Objectives: The aim of this study is to prioritize the preferences of women before and during pregnancy on receiving health information. Patients and Methods: This descriptive study was performed on pregnant women who had referred to health care centers affiliated to Semnan University of Medical Sciences, Iran in 2014. An anonymous self-administered questionnaire was developed. Results:The results showed that 17.5% (n = 35) of the participants reported their information needs about physical health to become pregnant, 36% (n = 72) psychological readiness for pregnancy and 57.5% (n = 115) domestic violence and its impact on the health of the mother and fetus. Number of previous delivery had a negative and significant relationship with the pregnant women's preferences (B = -1.31, P < 0.001). Conclusions: It is concluded that the most of pregnant women are oblivious to their health for getting pregnant and some of them experience symptoms of mental disorders in reproductive age. The findings show that domestic violence is a hidden and persistent epidemic among the pregnant women. Women, who had more previous delivery, needed this information less.

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Section: Discussionmentioning

confidence: 94%

Prioritizing Pregnant Women’s Preferences to Receive Health Information Before and During Pregnancy in Semnan in 2014 - 2015

Kahouei

Niaki

Homayoon

et al. 2016

Middle East J Rehabil Health Stud

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“…Recent randomized controlled trials among overweight women have had mixed results [26][27][28] . In some cases, intervention participants have improved adherence to dietary guidelines or increased physical activity without a difference in gestational weight gain or metabolic parameters [29][30][31] . A small pilot study (N=50) among non-diabetic, obese women found that intensive nutrition consultation reduced gestational weight gain, with a trend toward lower rates of gestational diabetes and pregnancy-induced hypertension 32 .…”

Section: Commentmentioning

confidence: 99%

537: Maternal BMI, glucose tolerance, and adverse pregnancy outcomes

Stuebe

2011

American Journal of Obstetrics and Gynecology

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Objectives-To estimate the association of pregravid body mass index (BMI), independent of 3-hour oral glucose tolerance test (OGTT) results, with pregnancy outcome.Study Design-In this secondary analysis of a cohort of women with untreated mild gestational glucose intolerance, defined as 50g glucose loading test between 135 and 199 mg/dL and fasting glucose <95 mg/dL, we modeled the association between pregravid BMI, OGTT results, and both pregnancy complications and neonatal adiposity. Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Results-Among NIH Public Access Author ManuscriptAm J Obstet Gynecol. Author manuscript; available in PMC 2013 July 01. LGA, and both maternal BMI and fasting glucose were associated with birth-weight z-score and neonatal fat mass.Conclusions-Among women with untreated mild gestational glucose intolerance, pregravid BMI is associated with increased gestational hypertension, birth weight and neonatal fat mass, independent of OGTT values.

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“…Seven randomized controlled trials, published between 2009 and 2012, are summarized in Table 1 [32][33][34][35][36][37][38]. In contrast to observational data, a recent summary of five of these studies concluded that they could find no clear effect on preventing GDM [39].…”

Section: Can Exercise Prevent Gdm?mentioning

confidence: 99%

The Role of Exercise in Reducing the Risks of Gestational Diabetes Mellitus

Hopkins

Artal

2013

Womens Health (Lond Engl)

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Women's Health (2013) 9(6), [569][570][571][572][573][574][575][576][577][578][579][580][581] support the demands of fetal growth. A progressive and marked insulin resistance develops in maternal skeletal muscle, beginning around mid-pregnancy and progressing during the third trimester to levels that approximate the insulin resistance seen in T2DM [9]. Hormones and adipo kines secreted from the placenta, including TNF-a, placental lactogen, placental growth hormone, cortisol and progesterone, are probable triggers of insulin resistance in pregnancy, owing to rapid reversal at delivery [10].Normal pregnancy is characterized by increased insulin secretion from pancreatic b cells to compensate for peripheral insulin resistance. This can be displayed as a hyperbolic relationship between insulin sensitivity (the inverse of insulin resistance) and insulin secretion from pancreatic b cells (Figure 2). The development of GDM occurs when a mother does not secrete enough insulin in order to be able to meet the metabolic stress of peripheral insulin resistance. The reciprocal relation ship is preserved in most GDM women, but occurs at much lower level of insulin secretion. That is, women with GDM secrete 40-70% less insulin for any degree of insulin resistance [11,12]. Therefore, pregnancy-induced insulin resistance may unmask the b-cell dysfunction characteristic of GDM [13].Serial assessments of insulin sensitivity starting before pregnancy have also demonstrated slightly greater insulin resistance persisting into the third trimester in women with GDM compared with normal pregnant women [11]. This resistance applies to both the action of insulin Gestational diabetes mellitus & maternal obesityGestational diabetes mellitus (GDM) is the most common medical complication of pregnancy and is defined as glucose intolerance or high blood glucose concentrations (hyperglycemia), with onset or first recognition during pregnancy. The prevalence of GDM varies from 1 to 20% and is rising worldwide in line with increasing trends of maternal obesity and Type 2 diabetes mellitus (T2DM) [1,2]. The incidence of GDM rises disproportionately with increasing obesity. A recent meta-analysis of 20 population-based studies estimated that the risk of developing GDM is 2.14-fold higher for overweight (BMI: 25.0-29.9), 3.56-fold higher for obese (BMI: ≥30.0) and 8.56-fold higher for severely obese women (BMI: ≥40.0) compared with normal weight pregnant women (BMI: <25.0) [3]. Obesity and GDM have been recognized as independent risk factors for a number of adverse maternal and fetal outcomes, including diabetes, hypertension, operative deliveries, macrosomia and neonatal complications [4][5][6]. More recently, we have begun to understand that maternal obesity and GDM are also associated with significant lifelong consequences for the next generation [7,8]. As obesity and GDM share many of the same health consequences, obese women and their offspring are at a greater risk for adverse outcomes (Figure 1). Pathophysiology of GDMDuring normal pregnancy,...

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Prevention of Gestational Diabetes

Cited by 127 publications

References 13 publications

Prioritizing Pregnant Women’s Preferences to Receive Health Information Before and During Pregnancy in Semnan in 2014 - 2015

Prioritizing Pregnant Women’s Preferences to Receive Health Information Before and During Pregnancy in Semnan in 2014 - 2015

537: Maternal BMI, glucose tolerance, and adverse pregnancy outcomes

The Role of Exercise in Reducing the Risks of Gestational Diabetes Mellitus

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