Prevention of hospital infections by intervention and training (PROHIBIT): results of a pan-European cluster-randomized multicentre study to reduce central venous catheter-related bloodstream infections

Kooi, Tjallie van der; Sax, Hugo; Pittet, Didier; Dissel, Jaap van; Benthem, Birgit van; Walder, Bernhard; Cartier, Vanessa; Clack, Lauren; Greeff, Sabine de; Wolkewitz, Martin; Hieke, Stefanie; Boshuizen, Hendriek C.; Kassteele, Jan van de; Abeele, A. Van den; Boo, Teck Wee; Diab-Elschahawi, Magda; Dumpis, Uga; Ghiță, Camelia; Fitzgerald, Susan; Lejko, Tatjana; Leleu, Kris; Martínez, Mercedes Palomar; Paniara, Olga; Patyi, Márta; Schab, Paweł; Raglio, Alfredo; Szilágyi, Emese; Ziętkiewicz, Mirosław; Wu, Albert W.; Grundmann, Hajo; Zingg, Walter

doi:10.1007/s00134-017-5007-6

Cited by 61 publications

(68 citation statements)

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“…Starting from the aspects related to our study of the correspondence between infection, section and pathogen, it is recommended the rapid, vigilant and targeted application of HAI prevention and control strategies for reducing infections in intensive care units [30][31][32][33][34][35], of surgical infections in the pre-, intra-and post-operative phase [36][37][38], reduction of urinary catheter infections [39][40][41], reduction of intravascular catheter infections [42,43], respectively, reduction infections with Clostridioides difficile [44].…”

Section: Discussionmentioning

confidence: 99%

Healthcare Associated Infections—A New Pathology in Medical Practice?

Voidăzan

Albu

Tóth³

et al. 2020

IJERPH

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Background: Hospital-acquired infections (HAI) contribute to the emotional stress and functional disorders of the patient and in some cases, can lead to a state of disability that reduces quality of life. Often, HAI are one of the factors that lead to death. The purpose of this study was to analyze the cases of HAI identified in public hospitals at the county level, through case report sheets, as they are reported according to the Romanian legislation. Methods: We performed a cross sectional study design based on the case law of the data reported to the Mures Public Health Directorate, by all the public hospitals belonging to this county. We tracked hospital-acquired infections reported for 2017-2018, respectively, a number of 1024 cases, which implies a prevalence rate of 0.44%, 1024/228,782 cases discharged from these hospitals during the studied period. Results: The most frequent HAIs were reported by the intensive care units (48.4%), the most common infections being the following: bronchopneumonia (25.3%), enterocolitis with Clostridioides difficile (23.3%), sepsis, surgical wound infections and urinary tract infections. At the basis of HAI were 22 pathogens, but the five most common germs were Clostridioides difficile, Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus. Bronchopneumonia have been most frequently reported in intensive care units, the most common being identified the Acinetobacter baumannii agent. Sepsis and central catheter infections also appeared predominantly in intensive care units, more often with Klebsiella pneumoniae. The enterocolitis with Clostridioides difficile, were the apanage of the medical sections. Infections with Staphylococcus aureus have been identified predominantly in the surgical sections at the level of the surgical wounds. Urinary infections had a similar distribution in the intensive care units, the medical and surgical sections, with Klebsiella pneumoniae being the most commonly incriminated agent. Conclusions: We showed a clear correspondence between the medical units and the type of HAI: what recommends the rapid, vigilant and oriented application of the prevention and control strategies of the HAI. Author Contributions: Data curation, S.V., S.A. and I.M.; Funding acquisition, B.G. and A.R.; Investigation, S.V., Réka Toth and I.M.; Methodology, S.V. and S.A.; Resources, R.T., B.G., A.R. and I.M.; Supervision, S.V., S.A. and I.M.; Visualization, R.T. and B.G.; Writing-original draft, S.V. and A.R.; Writing-review and editing, S.A. and B.G. All authors have read and agreed to the published version of the manuscript. Funding: This research received no external funding. Conflicts of Interest:The authors declare no conflict of interest.

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Section: Discussionmentioning

confidence: 99%

Healthcare Associated Infections—A New Pathology in Medical Practice?

Voidăzan

Albu

Tóth³

et al. 2020

IJERPH

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“…PROHIBIT evaluated the effectiveness of two evidence-based CRBSI reduction strategies in intensive care units (ICUs) across 14 hospitals in 11 European countries. The trial demonstrated that these interventions could improve process indicators and reduce CRBSI incidence densities 28. InDepth used a longitudinal qualitative case study design, gathering data from 6 of the 14 hospitals in the trial.…”

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confidence: 99%

Beyond barriers and facilitators: the central role of practical knowledge and informal networks in implementing infection prevention interventions

Szymczak

2018

BMJ Qual Saf

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“…Las prácticas como Higienización de las Manos (HM) y cuidados con catéteres son significativas en el proceso de atención al paciente y prevención de daños. Un estudio multicéntrico realizado en las UCI europeas demostró que la HM redujo, la incidencia de infección en la corriente sanguínea asociada al catéter venoso central, de 2,4/1.000 pacientes/día a 0,9/1.000 pacientes/día (p<0,0001) (2) . Entretanto, todavía hoy, se observa un contexto caracterizado por la ocurrencia de sucesivos daños provenientes de la práctica asistencial, que llevan al surgimiento de un vacío entre el cuidado que el paciente debería recibir y aquel que es realizado (3) .…”

Section: Introductionunclassified

Percepción del equipo de enfermería del clima de seguridad organizacional de un hospital público

Bezerra

Valim

Santos

et al. 2018

eglobal

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Objetivo: Avaliar a percepção da equipe de enfermagem sobre o clima de segurança organizacional em um hospital que é referência na região metropolitana da capital de Mato Grosso, Brasil, e verificar se houve diferença estatisticamente significante na percepção do clima de segurança organizacional entre as categorias dos auxiliares, técnicos de enfermagem e enfermeiros. Método: Estudo descritivo, transversal, com profissionais da enfermagem, por meio do questionário autoaplicável Safety Attitudes Questionnaire (SAQ), adaptado e validado para o Brasil. Resultados: A amostra foi composta por 139 profissionais de enfermagem. A média dos domínios do SAQ variou entre 42 a 73 pontos, classificada como baixa. A avaliação dos domínios evidenciou as menores médias para condições de trabalho e percepção da equipe de enfermagem sobre a gerência da unidade e gerência do hospital, respectivamente. Conclusão: Foi verificado baixa percepção do clima de segurança na instituição, visto que não foi alcançado escore satisfatório em nenhum dos domínios investigados, exceto para o domínio satisfação do trabalho, ainda assim, de forma limítrofe. Dessa forma, percebeu-se o distanciamento da administração do hospital e da gestão da unidade em atividades relacionadas à segurança do paciente, o que pode influenciar diretamente na adesão a comportamentos seguros pelos profissionais da equipe e diminuir a qualidade da assistência. Objetivo: Evaluar la percepción del equipo de enfermería del clima de seguridad organizacional en un hospital que es referencia en la región metropolitana de la capital de Mato Grosso, Brasil, y verificar si hubo diferencia estadísticamente significante en la percepción del clima de seguridad organizacional entre las categorías de los auxiliares, técnicos de enfermería y enfermeros.Método: Estudio descriptivo, transversal, con profesionales de enfermería, por medio del cuestionario auto aplicable Safety Attitudes Questionnaire (SAQ), adaptado y validado para el portugués del Brasil.Resultados: La muestra estuvo compuesta por 139 profesionales de enfermería. El promedio de los dominios del SAQ varió entre 42 a 73 puntos, clasificada como baja y la evaluación de los dominios evidenció las menores medias para condiciones de trabajo y percepción del equipo de enfermería sobre la gerencia de la unidad y gerencia del hospital, respectivamente.Conclusión: Se verificó una baja percepción del clima de seguridad en la institución, ya que no se alcanzó un puntaje satisfactorio en ninguno de los dominios investigados, excepto para el dominio satisfacción del trabajo, aún así, de forma limíte. De esta forma, se percibió el distanciamiento de la administracion del hospital y de la gerencia de las unidades relacionadas con la seguridad del paciente, lo que puede influir directamente en la adhesión a comportamientos seguros por los profesionales del equipo de salud y disminuir la calidad de la asistencia. Objective: To evaluate the perception of the nursing team regarding the organizational safety climate in a referral hospital in the metropolitan region of the capital of Mato Grosso, Brazil, and to verify whether there were statistically significant differences in the perception of the organizational safety climate among the nursing assistant, nursing technician and nurse categories. Method: A descriptive, transversal study with nursing professionals, using the self-administered Safety Attitudes Questionnaire (SAQ), adapted and validated for Brazil. Results: the sample consisted of 139 nursing professionals. The mean of the SAQ domains ranged from 42.07 to 73.13 points, classified as a poor perception. The evaluation of the domains evidenced lower means for working conditions and perception of management of the unit and of the hospital, respectively.Conclusion: There was a low perception of the organizational safety climate in the institution, since a satisfactory score was not achieved in any of the domains investigated, with the exception of the job satisfaction domain, although, in a borderline manner. In this way, it was possible to perceive the distancing of the hospital and unit management from activities related to patient safety, which can directly influence adherence to safe behaviors by the professionals of the team and decrease the quality of the care.

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Prevention of hospital infections by intervention and training (PROHIBIT): results of a pan-European cluster-randomized multicentre study to reduce central venous catheter-related bloodstream infections

Abstract: This study demonstrates that multimodal prevention strategies aiming at improving CVC insertion practice and HH reduce CRBSI in diverse European ICUs. Compliance explained CRBSI reduction and future quality improvement studies should encourage measuring process indicators.

Cited by 61 publications

References 38 publications

Healthcare Associated Infections—A New Pathology in Medical Practice?

Healthcare Associated Infections—A New Pathology in Medical Practice?

Beyond barriers and facilitators: the central role of practical knowledge and informal networks in implementing infection prevention interventions

Percepción del equipo de enfermería del clima de seguridad organizacional de un hospital público

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