Prevention of<i>Helicobacter pylori</i>infection in childhood

Yücel, Oya

doi:10.3748/wjg.v20.i30.10348

Cited by 43 publications

(36 citation statements)

References 58 publications

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“…Low socioeconomic status and poor sanitary standards have been considered as risk factors for the acquisition and transmission of H. pylori [21,22]. Our findings showed a significant relationship between H. pylori seropositivity and some variables related to socioeconomic status of their household such as monthly income, father's occupation and mother's education.…”

Section: Discussionsupporting

confidence: 52%

“…Epidemiological studies of H. pylori infection have always looked to find potential exposure variables in relation to individual hygiene as well as habits and life-style [22,23,27]. Our data showed no significant differences in H. pylori infection rates based on water source, regular latrine presence, regular hand washing before meal and having pets.…”

Section: Discussioncontrasting

confidence: 38%

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Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

Nguyen¹

2017

Ann Clin Lab Res

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Aim: H. pylori infection is predominantly acquired in early childhood. The aim of the present study was to determine the prevalence of H. pylori infection and to identify factors associated with the infection in Muong children living in Vietnam. Materials and methods:In a cross-sectional study 918 asymptomatic individuals of all generations living together in the same home were selected from 219 households, based on cluster sampling of residential location in Hoabinh Province, Vietnam. H. pylori infection status was determined by serology test on samples obtained at each visit. A questionnaire was filled out at the start of the study. H. pylori serology data were analyzed using χ 2 test and logistic regression models. Results Conclusion:The first community-based study in Muong population showed familial clustering in multi-generation population and supported the hypothesis of person-toperson transmission in H. pylori infection

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Section: Discussionsupporting

confidence: 52%

Section: Discussioncontrasting

confidence: 38%

Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

Nguyen¹

2017

Ann Clin Lab Res

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“…The adverse effects for the treatment were evident 7(9.9%) cases only in levofloxacin group while 10 cases (14%) in clarithromycin group had adverse effect for the regimen (Table 5). DISCUSSION Helicobacter pylori is a Class I carcinogen and the predominant bacterium that colonizes the stomach mostly during childhood [15,16] . Approximately 10% of infected individuals develop overt clinical disease while 90% remain subclinical and the infection can persist throughout life if untreated [17] .…”

Section: Methodsmentioning

confidence: 99%

Levofloxacin Versus Clarithromycin-Based Therapy for Eradication of Helicobacter Pylori Infection: A Comparative Study

elshahat¹

2019

Zagazig University Medical Journal

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Background: Helicobacter pylori (H.pylori) infection causes multiple upper gastrointestinal diseases but optimal therapeutic regimen which can eradicate infection in all the cases has not yet been defined. Antimicrobial resistance has decreased eradication rates for H.pylori infection worldwide. The aim of the present study was to compare between the efficacy and tolerability of levofloxacin versus Clarithromycin based triple therapy in eradication of H.pylori infection. Subjects and Methods: In this comparative cross sectional study, 142 patients with epigastric pain and dyspepsia and positive stool antigen test and only 35 of them were further confirmed by Rapid Urease Test during upper endoscopy (endoscopy was indicated) were enrolled. They were divided into 2 groups The first group (levofloxacin group) was treated with levofloxacin (500 mg daily) plus amoxicillin (1 gm twice a day) plus pantoprazol (40 mg twice daily) for 2 weeks. The second group (clarithromycin group) was treated with clarithromycin (500 mg twice a day) plus pantoprazol (40 mg twice daily) plus amoxicillin (1 gm twice a day) for 2 weeks. For treatment evaluation Stool antigen test was performed after four weeks after cessation of therapy. Results: H.pylori eradication was successful in 84.5% of the levofloxacin group and 69% of the clarithromycin group (P=0.001). The adverse effects were less frequent in levofloxacin-based than clarithromycin-based Ttiple therapy. Conclusion: Triple therapy with levofloxacin-based regimen has better efficacy than clarithromycin-based regimen.

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“…There have been several studies on associations of breastfeeding and Helicobacter infection. The majority of studies support a preventive association between breastfeeding and infection in infancy [67,68]. However, infection rates increase throughout childhood, suggesting that the protective effect of breastfeeding is limited to the early years of life.…”

Section: Helicobacter Pylorimentioning

confidence: 99%

Breastfeeding and the Risk of Infant Illness in Asia: A Review

Lee

Binns

2019

IJERPH

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Infancy remains the most vulnerable period of human life for death, illness, and establishing a lifetime trajectory of growth and health. It is estimated that there are 5.3 million deaths under five years of age worldwide and approximately 800,000 lives could be saved by improving breastfeeding rates and duration. In Asia, an estimated 300,000–350,000 child deaths could be prevented with optimal breastfeeding and the majority would be under 12 months of age. We present a systematic review of studies of infection and breastfeeding in infants in Asia and further review interactions of selected infectious diseases and breastfeeding. Initially, 2459 records of possible interest were identified, 153 full text papers were reviewed in detail, and 13 papers describing diarrhoeal disease and/or acute respiratory tract infection were selected for inclusion in the review. Additional papers were selected to discuss specific diseases and their relationship to breastfeeding. The review found that a variety of methods were used with differing definitions of breastfeeding and diseases. Overall, breastfeeding when compared to the use of infant formula, is associated with significantly lower rates of diarrhoeal disease and lower respiratory tract infection, with a reduction of 50% or more to be expected, especially in infants under six months of age. The relationship between breastfeeding and specific diseases including measles and HTLV1 were reviewed. Breastfeeding reduces some disease rates, but there remain a few conditions where breastfeeding may be contra-indicated.

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Prevention ofHelicobacter pyloriinfection in childhood

Cited by 43 publications

References 58 publications

Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

Levofloxacin Versus Clarithromycin-Based Therapy for Eradication of Helicobacter Pylori Infection: A Comparative Study

Breastfeeding and the Risk of Infant Illness in Asia: A Review

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