Prevention of infectious complications after minor gynaecological surgery

Ozolinya, Lyudmila A.; Lapina, I A; Bondarenko, K.R.

doi:10.20953/1726-1678-2016-1-16-20

Cited by 2 publications

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“…Озолини и соавт. [39] (n=70). Цель исследования -сравнение эффективности применения геля Метрогил Плюс (с метронидазолом и клотримазолом), который назначали согласно инструкции интравагинально по 5 г (1 полный аппликатор) 2 раза в сутки (утром и вечером) в течение 5 дней (n=35, 1-я группа) и вагинальных капсул Полижинакс (1 раз в сутки перед сном в течение 6 дней) (n=35, 2-я группа) после малых гинекологических операций для профилактики инфекционных осложнений.…”

Section: рис 4 динамика микрофлоры влагалища в процессе леченияunclassified

“…При бактериологическом исследовании до малой гинекологической операции достоверных различий между пациентками 1-й и 2-й групп не было выявлено: роста микрофлоры не отмечалось соответственно у 71,4 и 79,3% пациенток (р>0,05). Тем не менее авторы [39] обнаружили сочетанную инфекцию у каждой третьей пациентки в обеих группах, что делало вполне оправданным назначение антибактериальной терапии с профилактической целью. В контрольных бактериологических посевах из цервикального канала на 10-е сутки после операции выявлены достоверные различия показателей роста микрофлоры, которые отсутствовали у 79,3% пациенток 1-й группы (Метрогил Плюс) и у 94,3% женщин 2-й группы (Полижинакс) (p<0,05).…”

Section: рис 4 динамика микрофлоры влагалища в процессе леченияunclassified

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A review of international and Russian scientific data on the use of polygynax for the treatment and prevention of patients with nonspecific (aerobic), vulvovaginal candidiasis, and mixed vaginitis

Кира¹,

Savicheva²

2018

Ross. vestn. akush.-ginekol.

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The paper gives an analytical review of the results of recent researches into the etiology, diagnosis, treatment, and prevention of infectious and inflammatory diseases of the vagina and vulva. The characteristic feature of inflammatory diseases of the lower genital tract is shown to be the predominance of mixed infections, and the formation of various bacterial and bacterial-fungal associations in the vaginal biotope (associations of gram-positive, gram-negative bacteria and fungi of the genus Candida) leads to a change in the clinical picture and to the paucisymptomatic forms of the disease, which complicate diagnosis and treatment. The paper states the basic requirements for a drug for the rational therapy of vaginal and vulvar infectious and inflammatory diseases of mixed bacterial and fungal etiologies, which should have a wide range of antimicrobial activity and a non-suppressive effect on the normal vaginal microflora (lactobacilli, bifidobacteria). Polygynax is a vaginal combination drug designed in France, which meets the above requirements in composition (neomycin sulfate 35 000 IU, polymyxin B sulfate 35,000 IU, and nystatin 100,000 IU in one capsule). The paper gives the results of original investigations by both Russian and foreign authors, which have shown the high efficacy of Polygynax in the treatment of both bacterial and fungal vaginitis. The efficacy of polygynax is of value not only against C. albicans strains, but also against C. non-albicans ones resistant to other drugs. The local use of the drug prevents the development of resistance of the pathological microflora. Polygynax does not inhibit the growth of the vaginal Lactobacillus microflora. It is the drug of choice in the local treatment of vaginitis, especially when treatment should be initiated before the results of microbiological examination are available.

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Section: рис 4 динамика микрофлоры влагалища в процессе леченияunclassified

A review of international and Russian scientific data on the use of polygynax for the treatment and prevention of patients with nonspecific (aerobic), vulvovaginal candidiasis, and mixed vaginitis

Кира¹,

Savicheva²

2018

Ross. vestn. akush.-ginekol.

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Problematic issues of diagnosis and treatment of vulvovaginitis of mixed bacterial-candidiasis etiology

Беленичев

2021

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The aim of the study is to evaluate the effectiveness of modern antiseptic agent Gynodek in the treatment of mixed bacterial-candidiasis vulvovaginitis.Materials and methods. There were 67 patients with bacterial-candidiasis vulvovaginitis under observation. The diagnosis of candidiasis infection was verified according to the data of clinical and laboratory research methods. Patients received vaginal gel Gynodek 5 ml once a day for 7 days. The effectiveness of treatment was assessed according to the data of the clinical examination before treatment and on the 7th day of observation, and according to the laboratory (bacterioscopic, bacteriological) data before and after treatment. Complete clinical and bacterial debridement was criteria of the treatment effectiveness.Results and discussion. The clinical picture of bacterial-fungal vulvovaginitis was characterized by a decrease in the number and severity of symptoms such as hyperemia and edema of the mucous membrane, discharge from the genital tract was not typical.There were no complaints in 95.5% of the examined women after end of therapy, there were no objective symptoms in all women on the 7th day of treatment. Bacteriological examination after 2 weeks confirmed the therapy effectiveness in 86.6% of women. Peptostreptococcus spp. after treatment sowed at significant concentrations 106–107 CFU/ml only in 1.5% of patients, Streptococcus spp. in 8.9% of women, Candida albicans in 13.4%. Lactobacilli in the amount of 107 CFU/ml were in 86.6% of patients, which indicates a rapid restoration of normal vaginal microflora.Conclusions. Bacterial-fungal associations of microorganisms in the vaginal biotope lead to a complex clinical symptoms, which makes it difficult to make a timely diagnosis. Gynodek vaginal gel is highly effective against gram-positive, gram-negative and fungal microflora, which makes it the drug of choice in the treatment of bacterial-candidiasis vulvovaginitis. Gynodek creates a comfortable pH, promotes the rapid restoration of own lactoflora, and increases the functional activity of the vaginal mucosa epithelium, which ensures the prevention of vaginal infection recurrence.

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Prevention of infectious complications after minor gynaecological surgery

Cited by 2 publications

References 0 publications

A review of international and Russian scientific data on the use of polygynax for the treatment and prevention of patients with nonspecific (aerobic), vulvovaginal candidiasis, and mixed vaginitis

A review of international and Russian scientific data on the use of polygynax for the treatment and prevention of patients with nonspecific (aerobic), vulvovaginal candidiasis, and mixed vaginitis

Problematic issues of diagnosis and treatment of vulvovaginitis of mixed bacterial-candidiasis etiology

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