Prevention of ischemic stroke in clinical practice: a role of internists and general practitioners

Changes in the prevalence, management and treatment of hypercholesterolemia and other dyslipidemias over 10 years in Poland. The WOBASZ study

“…5 The remaining 85% to 90% of persons with hypercholesterolemia would require serious consideration of pharmacological treatment-lifelong in most cases. 6 There is a need for strengthening the motivation of doctors and patients to use the recommended types of lipid-lowering drugs in their effective doses, especially in patients at very high and high CVD risk. 7 About 10% to 15% of the adult population have isolated hypertriglyceridemia, which can mostly be controlled by diet and by increasing physical activity; however, if not effective, lipid--lowering treatment is recommended.…”

“…4 Also, the idea of CVD prevention, including the principles of hypercholesterolemia treatment, is being continuously promoted by other specialists. 6 There is solid evidence that increased concentrations of total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) in particular, are one of the main CVD risk factors and that hypertriglyceridemia and low high-density lipoprotein cholesterol (HDL-C) levels are regarded as independent risk factors for CVD. However, the recommended concentration of blood cholesterol depends on the level of 10-year risk of CVD death.…”

Atrial fibrillation in outpatients with stable coronary artery disease : results from the multicenter RECENT study

“…16, 34,36,37 We demonstrated that in outpatients with stable CAD and AF, the risk stratification of stroke and thromboembolism using the CHA 2 DS 2 -VASc score extends the recommendations for chronic antithrombotic therapy to a large proportion of patients (21%) who previously had no (or had less evidenced) indications for such a management according to the CHADS 2 score (<2). From the clinical point of view, these results indicate that invasive procedures (eg, elective percutaneous transluminal coronary angioplasty) performed in patients with stable CAD and AF should be preceded by a thorough analysis of bleeding risk to reduce the number of postprocedural bleeding events associated with simultaneous antithrombotic and antiplatelet therapy.…”

The Effect of Active and Non-Active Follow-Up of Patients on the Recurrence of Ischemic Stroke

“…The treatment of stroke may be divided into three parts: management in the acute phase by measures to restore the circulation and arrest the pathologic process, physical therapy and rehabilitation, and measures to prevent further strokes and progression of vascular disease (7). It is now a major goal of general medicine to reduce the incidence of stroke in the general population by the control of modifiable risk factors ("primary prevention") (8). In addition to reduction of known risk factors such as hypertension, smoking, and glucose control in diabetics (9), the widespread use of cholesterol-lowering statin medications and antiplatelet drugs has shown in some studies to reduce the primary incidence of and recurrence of stroke (10).…”