Prevention of malignant seeding at drain sites by hypofractionated radiotherapy in patients with pleural mesothelioma

Kara, Pınar Hanife; Uğur, Işıl; Misirlioğlu, Cem; Küçükplakçi, Bülent; Özgen, Aytül; Elgin, Yeşim; Demirkasimoğlu, Taciser; Sanri, Ergun

doi:10.1111/j.1743-7563.2010.01319.x

Cited by 6 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The role of teachers in the current era of globalization is to be able to design and select learning materials and learning strategies that are suitable for different backgrounds, as well as manage the learning process tactically and fun, be able to choose learning media, and design evaluation programs that are in accordance with educational objectives oriented towards mastering competencies (Idris et al, 2020). Depending on the educational context, it can be said that the definition of teacher professionalism focuses on the professional qualifications of teachers such as being good at their job, meeting the highest standards, and being able to achieve excellence (Demirkasimoglu, 2010). Baggini (2005) claims that for teachers today, professionalism is defined as the extent to which teachers overcome difficulties and the extent to which they can use their skills and experience related to their profession.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Education Policy Analysis in Order to Improve Teacher Professionalism

Nuraeni,

Widiana,

Ratnaya

2023

SLJIL

View full text Add to dashboard Cite

Teacher professionalism can be seen from its role in carrying out tasks, namely developing the potential of students with heterogeneous backgrounds, both basic abilities, social, economic and cultural. Today's teacher professionalism is still included in the "semi" or "quasi" professional category because their work, such as teaching, is not fully given autonomy rights in practice. Professionalism in relation to the right to autonomy for a teacher in carrying out his main duties as an educator and teacher includes the ability to plan, implement and evaluate learning. Meanwhile, without mastering various basic knowledge about science, about students, about the society and culture in which the school operates, learning theory, various learning models, and various evaluation models, it is difficult for teachers to easily adapt to the new demands of implementing national education keep changing. As for achieving the real category of teacher professionalism, teacher positions must require further education and special training, namely at least having a Bachelor's degree and continuing with specialized education in their field which currently can be pursued in teacher professional education (PPG).

show abstract

Section: Resultsmentioning

confidence: 99%

“…The concept of professionalism is used in different senses and is rather difficult to define (Kara et al, 2010). The term professionalism is currently widely used to classify the status of occupational groups in terms of honor (Kennedy et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Education Policy Analysis in Order to Improve Teacher Professionalism

Nuraeni,

Widiana,

Ratnaya

2023

SLJIL

View full text Add to dashboard Cite

show abstract

“…In the literature, the optimum dose and timing of RT has not been clear, however, based on retrospective studies hypo-fractionated RT has frequently been a preferred regimen. 19,26,30 The National Comprehensive Cancer Network (NCCN) recommends doses of 21 Gy in 3 fractions for prophylaxis. Although in recent years 21 Gy has been preferred in our department, the most used schedule being 36 Gy in 12 fractions.…”

Section: Discussionmentioning

confidence: 99%

Radiotherapy applications of patients with malignant mesothelioma: A single center experience

Akmansu

Erpolat

Göksel

et al. 2013

Reports of Practical Oncology & Radiotherapy

View full text Add to dashboard Cite

show abstract

“…Broadly speaking, five studies recommend PIT [3,6,[8][9][10], three studies state that PIT is unnecessary and one recent systematic review [2] concludes that there is a definite need for a high-powered RCT to assess the requirement for PIT as well as the optimum timing and dose. The existing RCTs have small sample sizes and were inadequately powered as they were based on an expected incidence of 40% tract metastases in the control arm.…”

Section: Clinical Bottom Linementioning

confidence: 99%

Should all patients who have mesothelioma diagnosed by video-assisted thoracoscopic surgery have their intervention sites irradiated?: Table 1

Nagendran

Pallis

Patel

et al. 2011

Interact CardioVasc Thorac Surg

View full text Add to dashboard Cite

A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was whether patients diagnosed with mesothelioma by video-assisted thoracoscopic surgery should have their intervention sites irradiated to prevent metastatic seeding. Altogether 334 papers were found using the reported search, of which nine represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. There is no general consensus in the literature. Four studies recommend prophylactic irradiation therapy (PIT), while three studies stated that PIT was unnecessary. A systematic review identified only three suitable randomized controlled trials (RCTs) from the literature. One trial found that 23% of radiotherapy (RT) patients developed tract metastases compared to 10% of control patients (P=0.748) with an estimated hazard ratio (RT to control) of 1.28 (95% CI: 0.29-5.73). Time from procedure to tract metastases was in fact shorter in patients treated with RT (2.4 months RT vs. 6.4 months control, non-significant). Another trial found that seeding of metastatic tumour to the intervention site occurred in 7% of RT sites vs. 10% of control sites (P=0.53). Freedom from tract metastasis survival was also non-significant between RT and control arms (P=0.82). However, the third trial reported a significantly greater incidence of intervention site metastases in control vs. RT patients (40% vs. 0%, respectively, P<0.001). Non-randomised studies found mixed results. One reported that median survival between patients with and without local metastases was not significantly different (P=0.64) while another article described no local metastases in PIT sites. None of the studies reported significant skin or side reactions and treatment was generally well tolerated. Based on the available evidence, we conclude that PIT is not currently justified.

show abstract

Prevention of malignant seeding at drain sites by hypofractionated radiotherapy in patients with pleural mesothelioma

Cited by 6 publications

References 18 publications

Education Policy Analysis in Order to Improve Teacher Professionalism

Education Policy Analysis in Order to Improve Teacher Professionalism

Radiotherapy applications of patients with malignant mesothelioma: A single center experience

Should all patients who have mesothelioma diagnosed by video-assisted thoracoscopic surgery have their intervention sites irradiated?: Table 1

Contact Info

Product

Resources

About