Prevention of Mother-to-Child Transmission of HIV in Yaounde: Barrier to Care

Landefeld, C. C.; Fomenou, L. A.; Ateba, Francis Ndongo; Msellati, Philippe

doi:10.1080/09540121.2017.1390540

Cited by 7 publications

(7 citation statements)

References 12 publications

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“…In countries of Sub-Saharan Africa (SSA) like Uganda, the risk of HIV infection during adolescence is high [2]. Moreover, vertical transmissions of HIV continue to occur in these countries due to low access to perinatal health care services [3]. As a result, the prevalence of HIV in Ugandan youth is on an upward trend.…”

Section: Introductionmentioning

confidence: 99%

Experiences and effects of HIV-related stigma among youth living with HIV/AIDS in Western Uganda: A photovoice study

Kimera

Vindevogel²,

Reynaert³

et al. 2020

PLoS ONE

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HIV-related stigma has been identified as a significant stressor affecting Quality of Life of Youth Living With HIV/AIDS (YLWHA). Gaining a contextualized understanding of how this stigma is experienced by YLWHA in Western Uganda is crucial in addressing it in this group and setting. In this study, we explored the lived experiences of YLWHA with HIV-related stigma. Photovoice was used to gain insight into the lived experiences of HIV-related stigma in 11 YLWHA (15-19 years), purposively selected from a hospital-based peer support group. Group interview transcripts, notes and photographs were subjected to phenomenological hermeneutic analysis. Encounters with enacted, anticipated and internalized stigmas and their myriad sequels were prevalent in the photos and narratives of participants. Our findings were categorized and presented in 5 main themes that were identified through the analysis: being devalued, experiencing fear, experiencing injustices, feeling lonely, and lacking future perspectives. HIV-related stigmas were experienced in various socio-ecological domains but predominantly in homes and schools that ought to be supportive surroundings for youths. A multilevel approach, targeting the entire society where the root causes of stigma can be found and specific contexts like schools and homes where youth are confronted with stigma on a daily basis is proposed for a wholistic intervention.

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Section: Introductionmentioning

confidence: 99%

Experiences and effects of HIV-related stigma among youth living with HIV/AIDS in Western Uganda: A photovoice study

Kimera

Vindevogel²,

Reynaert³

et al. 2020

PLoS ONE

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“…More than a decade since the implementation of the Prevention of Mother-to-Child Transmission (PMTCT) programme of HIV, more than 90% of pregnant women are said to know their HIV status, the percentage of women living with HIV accessing antiretroviral treatment is estimated to have increased from 65% in 2010 to 87% in 2018 and there has been an 84% reduction in HIV infected newborns [4][5][6][7][8][9]. However, despite these strides and advances in HIV care including universal test and treat [10,11], there is still persistence of incident maternal and newborn HIV infections [4][5][6][7][8][9]. Vertical transmission of HIV from mother to child can take place during pregnancy, delivery and lactation [12].…”

Section: Introductionmentioning

confidence: 99%

Socio-demographic associations of HIV among women attending antenatal care in selected rural primary care facilities in South Africa's Eastern Cape province.

Mabunda¹,

Sigovana

Chitha

et al. 2020

Preprint

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Background: To effectively reduce vertical HIV transmission requires a reduction of HIV prevalence and incidence among pregnant women and a full understanding of its epidemiology. The study aimed to determine the prevalence of HIV among women attending antenatal care and further determine spousal support during antenatal care attendance in rural areas in Eastern Cape province, South Africa. Methods: A Cross-sectional study of women attending antenatal care in four Primary Care facilities was conducted using an interviewer-administered questionnaire which collected information on socio-demographic characteristics and medical history. Binomial logistic regression analyses were used to determine factors associated with HIV and to estimate the prevalence ratio (PR). The 95% confidence interval (95%CI) is used for precision of estimates; p≤0.05 for statistical significance. Results: A total of 343 participants were included in the final analysis. The antenatal HIV prevalence was 38.2% (95%CI: 33.2 – 43.9). For 75% of the women, the HIV diagnosis was made 141 days before the date of the interview (median=77 days, interquartile range=42-141 days). Participants between the age of 30 to 39 years were 50% more likely to be HIV positive compared to those who were between the age of 20 to 29 years, these differences were statistically significant (PR=1.5; p-value=0.001). Furthermore, self-employed women were 30% less likely to be HIV positive when compared to unemployed participants, this was also statistically significant (PR=0.7; p-value<0.0001). Conclusion: Despite a 100% antenatal HIV testing rate, the antenatal HIV prevalence remains high in this population, coupled with no spousal attendance in antenatal care. It is important to move beyond awareness about the HIV status to actionable strategies of reducing the HIV incident cases. It is therefore important to remain vigilant and monitor mother-to-child transmission that could be associated with this increased prevalence.

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“…On the contrary a cross-sectional study in Zambiaand another in South Africa found no association between maternal decision making autonomy and adherence to infant prophylaxis [20,21]. In addition, a Cameroonian qualitative therapeutic itineraries study of barriers or impediments to ART adherence were found to include financial constraints, limited social support and limited information on HIV/AIDS and treatment [22].…”

Section: Introductionmentioning

confidence: 91%

Factors Influencing Maternal Adherence to Infant’s Nevirapine Prophylaxis in a Cross-Sectional Study Conducted at Mulago Hospital, Kampala, Uganda

Nabasirye¹,

Mawa²,

Ayebare³

2019

IJHPEBS

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To eliminate mother to child transmission of HIV, existing interventions might need to be scaled-up and rigorously implemented. One of the strategies to reduce vertical transmission of HIVis the 4-6weeks daily single oral dose ofNevirapine (NVP) or Zidovidinerecommended for newbornsto HIV positive mothers. Maternal optimal adherence to these anti-retroviral prophylaxis regimens is imperative to prevention of vertical transmission of HIV. Limited studies investigated maternal adherence to infant's NVP prophylaxis regimen and associated factors. This study examined the level and factors influencing maternal adherence to infant's NVPprophylaxis regimenat six weeks of age. Maternal adherence to infant's NVP regimen was defined as dispensation of 95% of the total daily single dose of NVPsuspension to infants at 6 weeks of age. Maternal adherence, socio-demographic and psychosocial factors were measured using a pre-tested questionnaire. Bivariate analysis and binary logistic regression model were used to determine the level and factors influencing maternal adherence to infant's NVP regimen respectively. Results showed that 77% of the mothers had optimal adherence. Maternal age ≥ 20 years and believe in the effectiveness of NVP in prevention of vertical transmission of HIV were associated with increased likelihood of adherence to infants NVP regimen (OR 6.18; 95% CI: 1.64-23.24) and (OR 12.69; 95% CI 3.07-52.44) respectively.In conclusion maternal maturity and perceived benefits of NVP seems to be important positive drivers of optimal adherence. This suggests the importance of considering psychosocial and demographic characteristics of mothers in policy and intervention designing.

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Prevention of Mother-to-Child Transmission of HIV in Yaounde: Barrier to Care

Cited by 7 publications

References 12 publications

Experiences and effects of HIV-related stigma among youth living with HIV/AIDS in Western Uganda: A photovoice study

Experiences and effects of HIV-related stigma among youth living with HIV/AIDS in Western Uganda: A photovoice study

Socio-demographic associations of HIV among women attending antenatal care in selected rural primary care facilities in South Africa's Eastern Cape province.

Factors Influencing Maternal Adherence to Infant’s Nevirapine Prophylaxis in a Cross-Sectional Study Conducted at Mulago Hospital, Kampala, Uganda

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