Prevention of Venous Thromboembolism

Clagett, G. Patrick; Anderson, Frederick A.; Geerts, William; Heit, John A.; Knudson, M. Margaret; Lieberman, Jay R.; Merli, Geno J.; Wheeler, H. Brownell

doi:10.1378/chest.114.5_supplement.531s

Cited by 447 publications

(285 citation statements)

References 341 publications

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“…29 However, venous thromboembolism is still the main cause of sudden death in hospital beds. 18 Prophylaxis is described as beneficial and, since groups of patients at low, moderate and high risk for the development of DVT can be identified, it is reasonable and desirable to consider prevention forms, which is much better than treatment. 9 Although accessible, prophylaxis for DVT is still underused, even in developed countries, as demonstrated in the study published by Goldhaber & Tapson, in which out of 2,726 patients diagnosed with DVT during their hospital stay, only 1,147 (42%) had been given prophylaxis over a 30-day period before diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…Studies by American and European groups defined detailed recommendations, which should be used in all classes of hospitalized patients. 9,18 Despite DVT prevention protocols being available for all health professionals, many do not use them routinely. 19,20 Our study aims at verifying whether DVT prophylaxis is being routinely and adequately used at a teaching hospital, working with the observational hypothesis that it is not performed according to current guidelines.…”

Section: Introductionmentioning

confidence: 99%

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Avaliação da utilização de profilaxia da trombose venosa profunda em um hospital escola

et al. 2007

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RESUMOContexto: A trombose venosa profunda (TVP) é uma doença freqüente e grave. A profilaxia é o melhor meio para reduzir a sua incidência, diminuindo a morbimortalidade gerada por suas complicações. Na relação custo x efetividade, é melhor manter uma rotina profilática do que tratar a doença já instalada. Objetivo: Verificar se a profilaxia da TVP está sendo utilizada de maneira adequada e rotineira no Hospital Escola Doutor José Carneiro (HEJC), de Maceió (AL). Métodos: Foi realizado um estudo transversal descritivo no HEJC durante o período de 6 meses. A amostra foi de 298 pacientes, de diferentes especialidades. Os dados foram coletados nos prontuários, divididos em clínicos (68,5%) e cirúrgicos (31,5%). Analisou-se, em cada paciente, como se procedeu a utilização da profilaxia para a TVP. Foram pesquisados fatores clínicos, medicamentosos e cirúrgicos para todos os pacientes e, com base nesses dados, foi realizada estratificação do risco conforme a classificação recomendada pela Sociedade Brasileira de Angiologia e Cirurgia Vascular (SBACV). O estudo estatístico foi realizado através do software SPSS, utilizando os testes qui-quadrado e de correção bivariada, considerando o valor de p < 0,05. Resultados: Dos 298 pacientes analisados, 204 eram da clínica médica, onde 28,9% eram de baixo risco, 60,3% médio risco e 10,8% alto risco para TVP; e 94 pacientes eram da clínica cirúrgica, onde 43,6% apresentaram baixo risco, 52,1% médio risco e 4,3% alto risco. Apenas 23% dos pacientes do grupo clínico e 2,1% para o grupo cirúrgico receberam a profilaxia de forma adequada.Conclusão: Apesar da eficácia da profilaxia para a TVP já ter sido comprovada e difundida, em nosso meio ainda não atinge os níveis desejados de utilização. Palavras-chave:Prevenção e controle, trombose venosa, avaliação. ABSTRACTBackground: Deep venous thrombosis (DVT) is a frequent and severe disease. Prophylaxis is the best means to reduce its incidence, lowering morbidity and mortality rates caused by its complications. In a cost-effectiveness ratio, it is better to maintain a prophylactic routine than to treat an established disease. Objective: To verify whether DVT prophylaxis is being properly and routinely used at Hospital Escola Doutor José Carneiro (HEJC), in Maceió, Brazil. Methods: A descriptive, cross-sectional study at HEJC was carried out for a 6-month period. The sample was composed of 298 patients within different specialties. Data were collected from medical records, and divided into clinical (68.5%) and surgical (31.5%). How DVT prophylaxis was performed was analyzed for each patient. Clinical, pharmacological and surgical factors were investigated for all patients. Based on these data, risk stratification was performed in accordance with the classification recommended by Sociedade Brasileira de Angiologia e Cirurgia Vascular. Statistical analysis was performed using software SPSS and the qui-square and bivariate correction tests, considering p value < 0.05. Results: Of the 298 patients analyzed, 204 belonged to medical clinic, ...

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Avaliação da utilização de profilaxia da trombose venosa profunda em um hospital escola

et al. 2007

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“…A incidência de TVP está aumentada nos pacientes submetidos à cirurgia abdominal ou pélvica 21,22 , ocorrendo em 25% dos pacientes sem profilaxia anticoagulante 21 . Na presença de doença maligna associada, a incidência de TVP é de, aproximadamente, 30%, e uma das principais causas de óbito em cirurgia de neoplasia ginecológica 22 .…”

Section: Desordens De Coagulação (Trombofilias)unclassified

Diretriz de Embolia Pulmonar

Volschan¹,

Caramelli²,

Gottschall³

et al. 2004

Arq. Bras. Cardiol.

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“…Patients harboring brain tumors are more likely to develop VTE than patients who have cancers in other sites (Table 1) . Studies have shown that other risk factors for VTE include age, sex, ethnicity, blood type, length of hospital stay, operative duration, and coagulation status [3,6,[8][9][10]14,[25][26][27][28][29][30][31][32][33][34][35][36][37][38]. Standard prophylactic measures for VTE include chemical anticoagulation, mechanical prophylaxis, and increased ambulation during the post-operative period [36,[39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54].…”

Section: Introductionmentioning

confidence: 99%

Venous Thromboembolism in Brain Tumor Patients: A Review of Literature

Coté¹,

Smith

2015

J Hematol Thrombo Dis

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Venous thromboembolism (VTE) is a relatively common and well-described condition, affecting approximately 1-2% of the general population. VTE can lead to significant morbidity and death via pulmonary embolism (PE). During the post-operative period, VTE occurs at higher rates due to natural thrombotic responses to injury and limited post-operative mobility. In general, rates of post-operative VTE are higher in patients undergoing operations for cranial and spinal lesions than for lesions of other types, a phenomenon that is not fully explained. Several studies have demonstrated that other risk factors for VTE include age, sex, ethnicity, hospital stay length, and coagulation state. Aggressive chemical and mechanical measures for VTE prophylaxis are indicated in the postoperative period to prevent the formation of VTE. Here we review the literature on VTE in brain tumor patients, with a focus on their etiology, diagnosis, treatment, and prophylaxis.

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Prevention of Venous Thromboembolism

Cited by 447 publications

References 341 publications

Avaliação da utilização de profilaxia da trombose venosa profunda em um hospital escola

Avaliação da utilização de profilaxia da trombose venosa profunda em um hospital escola

Diretriz de Embolia Pulmonar

Venous Thromboembolism in Brain Tumor Patients: A Review of Literature

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