Prévention secondaire des infarctus cérébraux liés à l’arythmie complète par fibrillation auriculaire : quel(s) traitement(s) et dans quel(s) délai(s) ?

Muresan, Ioan-Paul; Alamowitch, Sonia

doi:10.1016/j.praneu.2010.12.008

Cited by 1 publication

(4 citation statements)

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“…Our results supported data from a prospective multicentric study of 1125 patients nevertheless suffering from ischaemic stroke of all origin with a rate of 8.7% and this haemorrhagic transformation is significantly associated with large-sized infarct [27]. Ischaemic stroke recurrence in AF is assessed to be 2.5% and 5% at one week and one month respectively [2,3]. We reported recurrence rate of 2.9% at two weeks period.…”

Section: Discussionsupporting

confidence: 89%

“…Early haemorrhagic transformation risk in AF related stroke accounts for 2.7% at one week [3]. Our results supported data from a prospective multicentric study of 1125 patients nevertheless suffering from ischaemic stroke of all origin with a rate of 8.7% and this haemorrhagic transformation is significantly associated with large-sized infarct [27].…”

Section: Discussionsupporting

confidence: 87%

“…This relatively low rate of VKA use in our setting is partly due to physician's worry about bleeding risk and also geographic and financial constraints on accessing frequent International Normalized Ratio (INR) follow-up. However, new oral anticoagulants a great progress in therapeutics could be an alternative to VKA in a near future and modify our practice [3], due to their simpler way of use and comparative reduction of major bleeding risk [25,26].…”

Section: Discussionmentioning

confidence: 99%

“…Ischaemic stroke is a leading cause of acquired disability and death in adults [1]. Cardioembolic stroke accounts for 14-30% of all ischaemic strokes and appears to be associated with higher mortality and early recurrence [2,3]. Atrial fibrillation (AF) is the most common cardiac source of cerebral embolism with many associated risk factors [4,5].…”

Section: Introductionmentioning

confidence: 99%

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Non Valvular Atrial Fibrillation Related Ischaemic Stroke at the Teaching Hospital of Yalgado Ouédraogo, Burkina Faso

Germain¹,

Andre²,

Aristide³

et al. 2015

J Vasc Med Surg

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Objectives:We aim to describe the epidemiological and prognostic characteristics of non valvular atrial fibrillation related stroke. Patients and methods:We retrospectively analyzed data of hospitalized patients from January 1 st 2010 to June 30 th 2012 in the two contiguous departments of cardiology and neurology, at the teaching hospital of Yalgado Ouédraogo, Burkina Faso. Results:We recorded 391 cases of ischaemic stroke. Cardioembolic stroke was observed in 159 patients out of who, non valvular atrial fibrillation accounted for 43.5%. Atrial fibrillation was persistent/permanent in 60 cases (87%). The mean age ± SD was 63.3 ± 14.2 years (extremes: 26-91 years). Hypertension was observed in 85.5% of the cases. The mean CHA 2 DS 2 -VASc score was 4.72 ± 1.16. The mean HAS-BLED score was 2.35 ± 0.92 with a low to intermediate bleeding risk score (≤ 2) in 60.9 % of patients. The rate of vitamin K antagonists use was 52%. They were introduced at least a week after stroke onset in 34 cases. A mean follow up of two weeks in hospital noticed haemorrhagic transformation and ischaemic recurrence in respectively 8.7% and 2.9% of the cases. Mortality rate of 21.7% during hospitalization was predicted by large sized cerebral infarction and congestive heart failure (p<0.05). Conclusion:Non valvular atrial fibrillation stroke is associated with in-hospital high mortality and is subject to early recurrence.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 87%