Prevention strategy for antimicrobial resistance development in bacteria through milk and conservation of antibiotic sensitivity

Abstract

Residue of some antibacterial drugs persist at a lower concentration for prolonged time in milk of cows, buffaloes and goats after treatment of bacterial infections by antibacterial drugs following repeated or single dosing. Repeated dosing of antimicrobial agent is required to maintain therapeutic concentration for desirable period to cure mastitis and other bacterial infections. However, prolonged persistence of the antibiotic residue selectively preserves the resistant microorganism which triggers antimicrobial resistance development. Our recommended herbal preparations should be applied in milk producing animals towards production of safe milk as it is consumed by a large population and suckling animals. These herbal preparations have the potential to conserve antibiotic sensitivity which would keep the antibacterial drugs effective towards successful therapy of different bacterial infections in animals and human beings.