Preventive Action of Phospholipids on Decomposition of Methyl 13-Hydroperoxyoctadecadienoate

Abstract

Phospholipids. Antioxidant, Ascorbic Acid. Iron, 13-Hydroperoxyoctadecadienoic Acid Methyl EsterThe effects of phosphatidylcholine, phosphatidylethanolamine and phosphatidylserine on the thermal decom position of methyl 13-hydroperoxyoctadecadienoate were investigated in a chloroform/methanol mixture. Among the phospholipids tested, phosphatidylserine in hibited the thermal decomposition of methyl 13-hydro peroxyoctadecadienoate to about 30% after exposure to 60 °C for 48h wheareas only 10% remained in the ab sence of the phospholipid for the same heating period. Addition of eugenol with phosphatidylserine showed high synergistic activity which prevented the decomposi tion of the hydroperoxide to a higher extent under the same conditions. Phosphatidylserine was also found to inhibit iron -accelerated decomposition of methyl 13-hydroperoxyoctadecadienoate. Moreover, the decompo sition of the hydroperoxide accelerated by ascorbic acid was effectively prevented by a combination of eugenol and phosphatidylserine.