Preventive Interventions for Preterm Children

Guralnick, Michael J.

doi:10.1097/dbp.0b013e31824eaa3c

Cited by 83 publications

(32 citation statements)

References 107 publications

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“…The clinical and socio-economic characteristics described in this study may be useful to identify at-risk children that may benefit from early clinical and psychosocial interventions such as quality child care. 19 …”

Section: Discussionmentioning

confidence: 99%

Predictors of 2-year cognitive performance after laser surgery for twin-twin transfusion syndrome

Vanderbilt

Schrager

Llanes

et al. 2014

American Journal of Obstetrics and Gynecology

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Objective To determine risk factors for poor cognitive performance among children treated with in utero selective laser photocoagulation of communicating vessels for twin-twin transfusion syndrome (TTTS). Methods This was a prospectively enrolled cohort study. Cognitive performance at age 2 years (±6 weeks) was assessed via Battelle Developmental Inventory 2nd Edition (BDI-2). Multilevel regression models evaluated risk factors for poor cognitive performance at shared (“pregnancy”) and individual (“child”) levels. In addition to development, blindness, deafness and cerebral palsy were assessed based on physical exam. A priori power analysis determined that a sample of ≥100 children was required for adequate statistical power (0.80). Results 100 children (57 families) were evaluated. Total BDI-2 score was within normal range (mean=101.3, SD=12.2), with one child having a BDI-2 of <70. Individual child-level risk factors for lower BDI-2 included male sex (β=-0.37, p<0.01), lower head circumference (β=0.28, p<0.01), and higher diastolic blood pressure (β=-0.29, p<0.01). At the pregnancy level, lower maternal education (β=0.60, p<0.001), higher Quintero stage (β=-0.36, p<0.01), and lower GA at birth (β=0.30, p<0.01) were associated with worse cognitive outcomes. Donor/recipient status, GA at surgery, fetal growth restriction, and co-twin fetal demise were not risk factors. The rate of neurodevelopmental impairment (blindness, deafness, cerebral palsy, and/or a BDI-2 score <70) was 4%. Conclusion Overall cognitive performance quotients were in the normal range, with risk factors for poor outcomes seen at the pregnancy and child levels. Clinical and socio-economic characteristics can identify at-risk children needing additional interventions.

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Section: Discussionmentioning

confidence: 99%

Predictors of 2-year cognitive performance after laser surgery for twin-twin transfusion syndrome

Vanderbilt

Schrager

Llanes

et al. 2014

American Journal of Obstetrics and Gynecology

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“…One framework capable of unifying and integrating these diverse intervention efforts is the Developmental Systems Approach (DSA) (Guralnick, 2011, 2012). Although the structure and function of the DSA is similar to many other models in developmental science, it may offer a number of advantages when considering the future design of larger-scale comprehensive preventive intervention programs for children at risk due to environmental factors.…”

Section: Next Steps and The Developmental Systems Approachmentioning

confidence: 99%

Developmental Science and Preventive Interventions for Children at Environmental Risk

Guralnick

2013

Infants &Amp; Young Children

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The current status of preventive intervention programs for young children at environmental risk designed to reduce the school readiness gap is examined in the context of developmental science. A review of program effectiveness suggests that future progress may depend upon committing to a specific developmental approach consistent with the knowledge base of developmental science and establishing a generally agreed upon and unambiguous framework, set of goals, and associated mechanisms. The Developmental Systems Approach is suggested as one model that is consistent with developmental and existing intervention science, supporting an emphasis on program continuity, relationships, and comprehensiveness. A long-term plan for community-based systems development is presented.

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“…Assessment tools to gauge risk and protective factors at the levels of the child and family as well as intervention strategies are available that can be organized within and are consistent with this developmental framework. The developmental approach can also be applied to preventive intervention programs for children at risk for delays or disabilities, including children born preterm (Guralnick, 2012)…”

Section: Action Principles: International Consensusmentioning

confidence: 99%

International Human Rights to Early Intervention for Infants and Young Children With Disabilities

Brown

Guralnick

2012

Infants &Amp; Young Children

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With almost universal ratification of the Convention on the Rights of the Child and the growing number of States Parties that have signed or ratified the Convention on the Rights of Persons with Disabilities, the majority of countries in the world have now committed to implementing the human rights articulated in these treaties. In this article we first provide an overview of both Conventions, highlight the articles in the treaties that are relevant to early intervention for infants and young children with disabilities, and describe the specific duties required of States Parties to ensure compliance including international cooperation. Second, a series of early intervention action principles are put forward that can help States Parties translate the underlying values of the Conventions into practice.

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Preventive Interventions for Preterm Children

Cited by 83 publications

References 107 publications

Predictors of 2-year cognitive performance after laser surgery for twin-twin transfusion syndrome

Predictors of 2-year cognitive performance after laser surgery for twin-twin transfusion syndrome

Developmental Science and Preventive Interventions for Children at Environmental Risk

International Human Rights to Early Intervention for Infants and Young Children With Disabilities

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