Preventive treatment in migraine. Used drugs and related variables. Results of the European work and migraine survey

Vicente-Herrero, Ma Teófila; Torre, Mª. Victoria Ramírez-Iñiguez de la; Torre, Elena Ruíz-de la; Reinoso-Barbero, Luis

doi:10.24875/rmn.20000089

Cited by 5 publications

(9 citation statements)

References 18 publications

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“…Moreover, women are more likely to actively participate in online surveys [14]. A similarly high percentage of women has been reported in other large migraine surveys: 92% among Greek migraine patients [15], or 89.98% in the European Migraine & Headache Alliance (EMHA) survey conducted in various European countries [16]. The distribution of age groups and the average age in our sample, which was 39 years old, were similar to other large survey studies [17][18][19][20].…”

Section: Discussionsupporting

confidence: 87%

Migraine symptoms, healthcare resources utilization and disease burden in a large Polish migraine cohort

et al. 2023

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Background The Migraine in Poland study is the first large scale nationwide cross-sectional online survey of symptoms, approaches to management, treatment patterns, quality of life, and sociodemographic characteristics of the Polish migraine patients’ cohort, conducted from August 2021 to June 2022. Methods A cross-sectional online survey was designed based on the American Migraine Prevalence and Prevention (AMPP) Study. Participants were recruited through broad advertisement through various channels. The survey included questions allowing for the diagnosis of migraine without aura (MwoA) based on the third edition of the International Classification of Headache Disorders (ICHD-3). Moreover, the questionnaire assessed sociodemographic and headache features, comorbidities, consultation rates with medical professionals, as well as the use of abortive or preventive treatment, including non-pharmacological methods, psychological symptoms and the burden of migraine. Results A structured online questionnaire was submitted by 3225 respondents aged 13 to 80 (mean age 38.9, 87.1% women). In this group 1679 (52.7%) of participants fulfilled ICHD-3 diagnostic criteria for MwoA, which was in most cases (88.3%) confirmed by a medical professional in the past. In this group the average number of monthly headache days was 4.7, while 47.8% of participants had at least 4 migraine days per month. Mean Migraine Disability Assessment score was 42.65 (median 32). Among MwoA respondents, 1571 (93.6%) had consulted their headache with a medical professional in the past – mostly neurologists (n = 1450 (83.4%) and primary care physicians (n = 1393 (82.9%). In the MwoA cohort, 1553 (92.5%) of participants declared the current use of some form of treatment, although only 193 (11.5%) respondents were currently on preventive medications. The most prevalent comorbidities included: chronic rhinitis (37.1%), allergies (35.9%) and low blood pressure (26.9%). Anxiety (20.4%) and depression (21.3%) were highly prevalent among participants. Conclusions People with migraine in Poland face similar difficulties as their peers in other countries. Despite relatively high access to neurologist consultations and good diagnosis accuracy, migraine still poses diagnostic and therapeutic difficulties. In this context, migraine undertreatment in Polish population must be underlined, especially in context of high disease burden.

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Section: Discussionsupporting

confidence: 87%

Migraine symptoms, healthcare resources utilization and disease burden in a large Polish migraine cohort

et al. 2023

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“…The majority of our participants were females (92.4%) at a productive phase of their lives (73.9% were between 36 and 55 years old). These findings are in keeping with the majority of large epidemiological studies in migraineurs showing a clear and strong gender predominance of females over males, as demonstrated from the findings of a relatively recent survey conducted by the European Migraine & Headache Alliance (EMHA) in 3342 patients in Spain, Italy, France, Portugal, Ireland, the United Kingdom, Germany and other countries of the European Union, where it was demonstrated that over 85% of participants were middle-aged females [16]. However, an interesting finding of our current survey was that about one third of participants had their first migraine attack before the age of 18.…”

Section: Discussionsupporting

confidence: 89%

Results of a Web-Based Survey on 2565 Greek Migraine Patients in 2023: Demographic Data, Imposed Burden and Satisfaction to Acute and Prophylactic Treatments in the Era of New Treatment Options

Dermitzakis,

Argyriou,

Bilias

et al. 2024

JCM

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Objective: The Greek Society of Migraine and Headache Patients conducted its third in-line population web-based survey in 2023 to ascertain if the burden of the disease and the patients’ satisfaction with conventional and novel migraine therapies are changing compared to our previous findings from 2018 and 2020. Methods: The sampling process was based on a random call to participants to reply to a specific migraine-focused self-administered questionnaire, including 83 questions in Greek, which was distributed nationwide through the online research software SurveyMonkey. Results: We eventually enrolled 2565 patients, the majority of which were females. Our findings clearly demonstrate that migraine is still a burdensome condition. The degree of its impact on all aspects of productivity depends on the monthly frequency of migraine and the response rates to acute and prophylactic treatments. A total of 1029 (42.4%) of the patients had visited the emergency room mainly for unresponsiveness to acute treatments or aura-related symptoms. Triptans seem to be partly effective as acute therapies. OnabotulinumtoxinA seems to be effective for almost half of chronic migraine patients (43.9%) to report adequate satisfaction with this treatment (27.8% were “fairly happy”, 10.6% were “very happy”, and 5.5% were “extremely happy”). Due to their high rates of preventative effectiveness, most respondents treated with anti-CGRP Mabs expressed their optimism concerning their future while living with their migraine (88.25%), as well as towards further improvements in their quality of life (82.8%) status, mostly with fremanezumab. Conclusions: The patients recognize the usefulness of anti-CGRP Mabs in migraine prevention and consequently seem to be more optimistic than before about living with migraine. Considering the market change that is anticipated with the use of gepants and ditans, larger longitudinal population-based studies are warranted to further explore if the new era of migraine therapeutics might further lessen the burden of the disease.

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“…Nonetheless, our results confirm that the vast majority of patients with migraine are women. The corresponding percentage in the first similar survey (GSMHP conducted in 2018) was 93% [ 13 ] vs 92% in the current, while a survey from the European Migraine & Headache Alliance (EMHA) conducted in various European countries, recorded a percentage 89.98% of women [ 15 ]. Nonetheless, this overwhelming gender predominance of female over male respondents in the current and 2018 [ 13 ] settings, might also be explained by the assumption that female patients with migraine are likely more active in social media; thus, being more affable to actively participate in online, web-based surveys.…”

Section: Discussionmentioning

confidence: 99%

Results of a Web-based survey of 2105 Greek migraine patients in 2020: demographics, clinical characteristics, burden and the effects of the COVID-19 pandemic on the course of migraine

Dermitzakis

Kouroudi²,

Spingos

et al. 2022

BMC Neurol

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The Greek Society of Migraine and Headache Patients (GSMHP), maintaining a strong commitment to research and information, conducted its second web-based online survey named "Migraine in Greece—2020", following its first one conducted in 2018. The 2020 study included 2,105 migraine patients who were called to answer 151 questions. The purposes of the current research were to record the demographic and clinical characteristics of migraine patients in Greece, including the severity and effects of migraine on respondents' quality of life, as well as to survey the effects of the coronavirus pandemic on the course of migraine. Our population, internet-based study provides data that will hopefully contribute to better comprehend the clinical phenotype and course of migraine during the COVID-19 pandemic.

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Preventive treatment in migraine. Used drugs and related variables. Results of the European work and migraine survey

Cited by 5 publications

References 18 publications

Migraine symptoms, healthcare resources utilization and disease burden in a large Polish migraine cohort

Migraine symptoms, healthcare resources utilization and disease burden in a large Polish migraine cohort

Results of a Web-Based Survey on 2565 Greek Migraine Patients in 2023: Demographic Data, Imposed Burden and Satisfaction to Acute and Prophylactic Treatments in the Era of New Treatment Options

Results of a Web-based survey of 2105 Greek migraine patients in 2020: demographics, clinical characteristics, burden and the effects of the COVID-19 pandemic on the course of migraine

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