“…Manca and coauthors (Manca and Grana, 2010;Manca et al, 2011;Manca, 2012Manca, , 2013aManca, , 2013bManca, , 2014 proposed the following DEPs to assess the economic sustainability of an HDA plant: Where N P ,N R are the number of (by)products and raw materials; C,F are the price/ cost of process streams and their corresponding flowrates; nHpM,nEquip are the number of production hours in a month and the number of process units involved in the EA; W,IC are the electric power absorbed by a specific unit and the investment cost of equipment; S, H 2 O, FO are the subscripts that identify respectively the steam used in the reboilers of the distillation columns, the water used in the condensers of those columns, and the fuel oil used in the furnace of the HDA plant (see also http:// pselab.chem.polimi.it/ for further details). Equations (25.5)e(25.7) can be extended/ adapted to any chemical process.…”