Prick testing for allergens standardized by using a precision needle

Brown, H. Morrow; Su, Song‐Nan; Thantrey, Nazra

doi:10.1111/j.1365-2222.1981.tb01571.x

Cited by 42 publications

(19 citation statements)

References 5 publications

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“…Subjects were then skin tested on one forearm according to standard procedures (18). Four common seasonal and perennial allergen solutions in 50% glycerin were used (Miles Inc., Elkhart).…”

Section: Methodsmentioning

confidence: 99%

A Minnesota Multiphasic Personality Inventory profile of women with allergic rhinitis.

Gauci

King

Saxarra

et al. 1993

Psychosomatic Medicine

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The aim of this study was to explore relationships among perennial allergic rhinitis and personality traits in a nonpsychiatric female population of proven allergic status. Female subjects were assigned to the allergic (N = 22) or nonallergic group (N = 18) on the basis of skin prick test and self-reported allergic status. Analysis of MMPI profiles showed that allergic subjects scored significantly higher on the Hypochondriasis (Hs) and Social Introversion (Si) scales and significantly lower on the Correction (K) and Ego Strength (Es) scales. The results suggested that women with perennial allergic rhinitis show poorer psychological functioning than nonallergic women. In addition, the number of allergies was positively correlated with T scores on the Hs, Depression (D), Hysteria (Hy), Psychasthenia (Pt), Schizophrenia (Sc), Si, and Conscious Anxiety (A) scales, and negatively correlated with T scores on the K and Es scales. Skin reactivity to house dust mite and grass pollen allergens were positively correlated with scores on Si, whereas skin reactivity to grass pollen and mold allergens was positively correlated with D and Pt (grass) and Pd and Sc (grass and mold). Two possible mechanisms explaining the link between psychological factors and allergic rhinitis include (1) the effect of cortisol on IgE production or (2) the production of mediators during an allergic reaction which travel from the nose to the brain.

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“…Subjects were then skin tested on one forearm according to standard procedures (18). Four common seasonal and perennial allergen solutions in 50% glycerin were used (Miles Inc., Elkhart).…”

Section: Methodsmentioning

confidence: 99%

A Minnesota Multiphasic Personality Inventory profile of women with allergic rhinitis.

Gauci

King

Saxarra

et al. 1993

Psychosomatic Medicine

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“…Prick tests against a battery of food and environmental allergen extracts (Bencard) were performed on all patients using the Mor row Brown Standardised needle [9]; a weal diameter 3 mm greater than that caused by the diluent control within 15 min was consid ered positive.…”

Section: Skin Testsmentioning

confidence: 99%

Relevance of Milk- and Egg-Specific IgG4 in Atopic Eczema

Shakib

Brown

Stanworth

1984

Int Arch Allergy Immunol

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In a substantial proportion of atopic eczema patients clinical sensitivity to food is not confirmable by either skin prick test or IgE RAST. The diagnosis of provocative food factors in this condition is, therefore, highly dependent on dietary manipulations which are time consuming and sometimes dangerous. In an attempt to find an alternative laboratory procedure we have questioned the clinical relevance of specific IgG4 measurement in the sera of these patients in the light of previous reports demonstrating raised total serum IgG4 in patients with atopic eczema. Thus, a highly reliable ELISA was developed to measure IgG4 specific to 3 cow’s milk proteins and 2 hen’s egg proteins in the sera of milk- and egg-allergic eczema patients and non-eczematous controls. The study provides clear evidence showing that the detection of milk- and egg-specific IgG4 in atopic eczema patients has no clinical value.

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“…The (modified) Prick-Test [53] is completed by applying a bead of allergen solution on top of the skin and pricking into the skin with a needle (or lancet) in the area of the bead [54], [55]. In this way parts of the allergen solution are inserted through the epidermal barrier into the corium by the lancet.…”

Section: Diagnostic Methods For Early Diagnosis Of Allergiesmentioning

confidence: 99%