Primary actinomycosis of the thigh – a rare soft tissue infection with review of literature

Khandelwal, Rohan; Jain, Ila; Punia, Sudhanshu; Singh, Arshdeep; Yadav, Siddharth; Sharma, Piyush; Singh, Shailendra; Mohanty, Pranita

doi:10.1258/shorts.2012.011137

Cited by 4 publications

(3 citation statements)

References 7 publications

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“…Most patients have progressive skin and soft-tissue inflammation, which can become an abscess or cold mass, or nodular lesions with fistulas that need to be differentiated from chronic inflammatory skin disease, cutaneous mycobacterial infections, and sporotrichosis. 85 , 86 …”

Section: Clinical Features Of Actinomycosismentioning

confidence: 99%

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Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

Valour¹,

Sénéchal²,

Dupieux³

et al. 2014

IDR

386

457

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Actinomycosis is a rare chronic disease caused by Actinomyces spp., anaerobic Gram-positive bacteria that normally colonize the human mouth and digestive and genital tracts. Physicians must be aware of typical clinical presentations (such as cervicofacial actinomycosis following dental focus of infection, pelvic actinomycosis in women with an intrauterine device, and pulmonary actinomycosis in smokers with poor dental hygiene), but also that actinomycosis may mimic the malignancy process in various anatomical sites. Bacterial cultures and pathology are the cornerstone of diagnosis, but particular conditions are required in order to get the correct diagnosis. Prolonged bacterial cultures in anaerobic conditions are necessary to identify the bacterium and typical microscopic findings include necrosis with yellowish sulfur granules and filamentous Gram-positive fungal-like pathogens. Patients with actinomycosis require prolonged (6- to 12-month) high doses (to facilitate the drug penetration in abscess and in infected tissues) of penicillin G or amoxicillin, but the duration of antimicrobial therapy could probably be shortened to 3 months in patients in whom optimal surgical resection of infected tissues has been performed. Preventive measures, such as reduction of alcohol abuse and improvement of dental hygiene, may limit occurrence of pulmonary, cervicofacial, and central nervous system actinomycosis. In women, intrauterine devices must be changed every 5 years in order to limit the occurrence of pelvic actinomycosis.

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Section: Clinical Features Of Actinomycosismentioning

confidence: 99%

“…In patients with primary skin and soft-tissue actinomycosis, abscesses have to be drained and prolonged antimicrobial therapy is required to achieve cure. 85 , 86 …”

Section: Clinical Features Of Actinomycosismentioning

confidence: 99%

Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

Valour¹,

Sénéchal²,

Dupieux³

et al. 2014

IDR

386

457

View full text Add to dashboard Cite

show abstract

“…The most common symptoms of cutaneous actinomyosis are having progressive skin and soft-tissue inflammation, which can become an abscess or cold mass, or nodular lesions with fistulas that need to be differentiated from chronic inflammatory skin disease, cutaneous mycobacterial infections, and sporotrichosis. 7 Basically the diagnosis of Cutaneous Actinomycosis is made by the following tests and exams: 8 i) A thorough physical examination and assessment of symptoms. ii) Evaluation of the affected individual’s medical history.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Actinomycosis and Long-Term Management Through Using Oral and Topical Antibiotics: A Case Report

Najmi

Najmi²,

Tawhari

et al. 2018

Clinics and Practice

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Actinomycosis is a subacute or chronic suppurative bacterial infection which caused because of filamentous gram-positive, anaerobic to microaerophilic nonacid fast bacilli primarily of the genus Actinomyces that normally colonize the mouth, colon, and vagina. Primary cutaneous actinomycosis is a rare entity and is generally associated with trauma. A 61- year-old Yemeni male firstly presented to the surgical department in King Fahd Central Hospital with multiple swelling, petted lesions and boring of sensation in the right foot. Local examination showed multiple erythematous nodules and plaques with discharge in the right leg, and active sinus was not determined.

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Actinomycosis: Current State of the Problem. Features of the Course and Laboratory Diagnostics

Ткаченко,

Коваленко,

Ткаченко

2024

ІХ

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Актиномікоз – це гранулематозне захворювання, яке повільно прогресує і може виникати як у людей з ослабленим імунітетом, так і в імунокомпетених осіб. Ця інфекція є ендогенною, а її збудники – актиноміцети – постійними мешканцями різних екологічних ніш організму людини. Крім порожнини рота, де вони переважають серед інших бактерій, актиноміцети є представниками мікробіоти кишечнику, сечостатевих шляхів і шкіри. За останні роки було ідентифіковано велику кількість нових видів Actinomyces. Із впровадженням сучасних методів дослідження знання про їхню клінічну значимість поступово накопичуються, також розширюється спектр захворювань, пов’язаних з актиноміцетами. Виявлення та ідентифікація збудників у клінічних мікробіологічних лабораторіях може бути складним завданням, а результати посіву можуть бути хибно негативними, особливо, якщо матеріал відбирали після початку антибіотикотерапії. Використання сучасних гістопатологічних і молекулярних методів діагностики допомагає подолати ці проблеми. Огляд літератури акцентує увагу на питаннях актиномікозної інфекції, корисних для клініцистів різного профілю. Надається етіологічна характеристика збудників, розглядаються найбільш поширені та атипові клінічні форми, які реєструються у різних країнах останнім часом, описуються сучасні діагностичні методи та напрямки лікування хворих на актиномікоз.

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Primary actinomycosis of the thigh – a rare soft tissue infection with review of literature

Cited by 4 publications

References 7 publications

Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

Cutaneous Actinomycosis and Long-Term Management Through Using Oral and Topical Antibiotics: A Case Report

Actinomycosis: Current State of the Problem. Features of the Course and Laboratory Diagnostics

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