Primary adrenal and chest wall tuberculosis presenting as an adrenal crisis

Jang, Seol A; Park, J.H.; Lee, K.A.

doi:10.1093/qjmed/hcx089

Cited by 5 publications

(5 citation statements)

References 4 publications

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“…Except for salt craving, the symptoms of primary adrenal insufficiency are rather nonspecific and include weakness, fatigue, musculoskeletal pain, weight loss, abdominal pain, depression and anxiety [ 6 ]. As a result, the diagnosis is frequently delayed, resulting in a clinical presentation with an acute life-threatening adrenal crisis [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

“…According to a retrospective analysis of autopsies and adrenalectomies reviewed by K Y Lam and C Y Lo, the adrenal gland was the only extra-pulmonary organ involved by tuberculosis in 14 of these 55 patients (25%; 35 men and 20 women).They found that unexpected and extra-pulmonary tuberculosis such as adrenal tuberculosis has been a common problem [ 5 ]. Adrenal tuberculosis is difficult to diagnose due to non-specific symptoms [ 6 ]. The diagnosis is therefore often delayed.…”

Section: Introductionmentioning

confidence: 99%

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An autopsy case of unexpected death due to Addison’s disease caused by adrenal tuberculosis

Zhao

Gao

et al. 2021

Eur J Med Res

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Background Adrenal tuberculosis is difficult to diagnose due to non-specific symptom. Unexpected death due to adrenal insufficiency after trauma surgery is rare. Case presentation A 45-year-old man, who was admitted to hospital because of trauma to the right hand, died unexpectedly on the 13th day after replantation of amputated fingers. He was diagnosed with brain edema and diluted hyponatremia. Autopsy and histopathologic examination revealed severe brain edema combined with cerebellar tonsillar hernia, extensive destruction of adrenal gland caused by bilateral adrenal tuberculosis and right lung invasive pulmonary tuberculosis. Conclusions Trauma and pulmonary tuberculosis complicated with adrenal tuberculosis induced the adrenal crisis, which eventually lead to severe cerebral edema and hernia, and finally death from respiratory and circulatory failure. This autopsy and histopathologic examination suggested a possible pathophysiologic mechanism of sudden death due to diluted hyponatremia after trauma surgery.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

An autopsy case of unexpected death due to Addison’s disease caused by adrenal tuberculosis

Zhao

Gao

et al. 2021

Eur J Med Res

View full text Add to dashboard Cite

show abstract

“…Except for salt craving, the symptoms of primary adrenal insu ciency are rather nonspeci c and include weakness, fatigue, musculoskeletal pain, weight loss, abdominal pain, depression and anxiety [4]. As a result, the diagnosis is frequently delayed, resulting in a clinical presentation with an acute lifethreatening adrenal crisis [6].…”

Section: Discussionmentioning

confidence: 99%

“…It was reported that the adrenal gland was the only extra-pulmonary organ involved by tuberculosis in 14 of these 55 patients (25%;35 men and 20 women) [3]. Adrenal tuberculosis is di cult to diagnose due to non-speci c symptoms [4]. The diagnosis is therefore often delayed.…”

Section: Introductionmentioning

confidence: 99%

An Autopsy Case of Sudden Death Due To Adrenal Crisis Caused By Pulmonary Tuberculosis Complicated With Adrenal Tuberculosis

Zhao¹,

Gao²,

Ni³

et al. 2021

Preprint

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Background: Adrenal tuberculosis is difficult to diagnose due to non-specific symptom. Sudden death due to adrenal crisis after trauma surgery is rare to be seen.Case presentation: A 45-year-old man, who was admitted to hospital because of trauma of right hand, died suddenly on the 13th day after replantation of amputated fingers. He was diagnosed with brain edema and diluted hyponatremia. Autopsy and histopathologic examination revealed severe brain edema combined with cerebellar tonsillar hernia, extensive destruction of adrenal gland caused by bilateral adrenal tuberculosis and right lung invasive pulmonary tuberculosis. Conclusions:Trauma and pulmonary tuberculosis complicated with adrenal tuberculosis induced the adrenal crisis, which eventually lead to severe cerebral edema and hernia, and finally death from respiratory and circulatory failure. This autopsy and histopathologic examination suggested a possible pathophysiologic mechanism of sudden death due to diluted hyponatremia after trauma surgery.

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“…An electronic search based on PubMed was carried out using "adrenal tuberculosis" in title/abstract. After excluding autopsy reports, we identified a total of 19 cases [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]. The clinical characteristics, diagnosis, and treatment of these patients were summarized in Table 2.…”

Section: Literature Reviewmentioning

confidence: 99%

Adrenal Tuberculosis: A Case Report and Literature Review

Hao

Gao

et al. 2023

Urol Int

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Adrenal tuberculosis (TB) is a rare disease, which is difficult to diagnose because of its atypical symptoms. We reported a 41-year-old female who was admitted to hospital due to a left adrenal tumor, which was found in health examination without any symptoms. Abdominal CT showed a mass in her left adrenal. The results of blood test were normal. A retroperitoneal laparoscopic adrenalectomy was carried out, and adrenal TB was finally pathologically diagnosed. Following this, examinations focusing on TB were conducted which revealed negative results except for T-cell enzyme-linked immunospot. After the operation, the hormone level was normal. However, a wound infection occurred, which was recovered after antituberculosis treatment. In conclusion, even if there is no evidence of TB, we should be alert when diagnosing adrenal masses. Examinations of pathology, radiography, and hormone play important roles in determining the definite diagnosis of adrenal TB.

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Primary adrenal and chest wall tuberculosis presenting as an adrenal crisis

Cited by 5 publications

References 4 publications

An autopsy case of unexpected death due to Addison’s disease caused by adrenal tuberculosis

An autopsy case of unexpected death due to Addison’s disease caused by adrenal tuberculosis

An Autopsy Case of Sudden Death Due To Adrenal Crisis Caused By Pulmonary Tuberculosis Complicated With Adrenal Tuberculosis

Adrenal Tuberculosis: A Case Report and Literature Review

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