Primary and Secondary Amenorrhea

D'Adamo, Ebe; Diesse, Laura; Giorgis, Tommaso de; Chiarelli, Francesco; Mohn, Angelika

doi:10.5772/17675

Cited by 5 publications

(1 citation statement)

References 104 publications

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“…Selama 2 tahun pertama setelah menstruasi, menstruasi sering tidak normal karena tidak matangnya aksis hipotalamus-hipofisis-ovarium. Dari sudut pandang kedokteran barat siklus menstruasi normal didasarkan pada sistem umpan balik yang kompleks antara hipotalamus, kelenjar pituitari, dan ovarium, serta reaksi siklus pada lapisan rahim (endometrium) (Chiavaroli et al 2011).…”

Section: Pendahuluanunclassified

Secondary Amenorrhea Therapy With Accupuncture And Turmeric - Fenugreek Herbal

2017

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Background: Secondary amenorrhea is a condition when period cycle of women with irregular menstruation disappeared within six months in a row or; when the period cycle of regular menstruation women disappeared during three months in a row. In Traditional Chinese Medicine (TCM), amenorrhea is known as Jing Bi. The patient in this study case was having secondary amenorrhea with menstrual complaints not within 3 months and 22 days after the last periods. Patient was classified as secondary amenorrhea with differentiation of Qi and blood deficiency syndrome. Purpose: To know the effect of acupuncture therapy with Sanyinjiao point (SP6), Taichong point (LR3), Zusanli point (ST36), Gui lai point (ST 29) combined with turmeric herbal therapy (Curcuma domestica Val) and klabet seed (Trigonella foenum-graecum L.) in patients with secondary amenorrhea. Methods: Treatment of this secondary amenorrhea case was using acupuncture and herbal therapy. Acupuncture therapy at acupoint Sanyinjiao (SP6), Taichong (LR3), Zusanli (ST36), and Gui Lai (ST29) with tonification principle of Qi and blood and improve menstrual flow. The herbal therapy given were turmeric (Curcuma domestica Val) and fenugreek seeds (Trigonellafoenum-graecum L.), which has estrogenic effect. Results: Estrogen stimulates the lining of the uterus to remove the menstrual blood. In the treatment of secondary amenorrhea, acupuncture therapy was given 21 times, three times a week. Herbal therapy was given for 60 days, taken 2 times a day with dose of 15 grams of turmeric and 4 grams of fenugreek seeds. This therapy might help the menstrual blood exuviation. Conclusion: Acupuncture and herbal therapy can be applied continously to the patient up until regular period cycle are attained.

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Section: Pendahuluanunclassified

Secondary Amenorrhea Therapy With Accupuncture And Turmeric - Fenugreek Herbal

2017

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Genomic Markers of Ovarian Reserve

Wood¹,

Rajkovic

2013

Semin Reprod Med

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Ovarian reserve and its utilization, over a reproductive life span, are determined by genetic, epigenetic, and environmental factors. The establishment of the primordial follicle pool and the rate of primordial follicle activation have been under intense study to determine genetic factors that affect reproductive lifespan. Much has been learned from transgenic animal models about the developmental origins of the primordial follicle pool and mechanisms that lead to primordial follicle activation, folliculogenesis, and the maturation of a single oocyte with each menstrual cycle. Recent genome-wide association studies on the age of human menopause have identified approximately 20 loci, and shown the importance of factors involved in double-strand break repair and immunology. Studies to date from animal models and humans show that many genes determine ovarian aging, and that there is no single dominant allele yet responsible for depletion of the ovarian reserve. Personalized genomic approaches will need to take into account the high degree of genetic heterogeneity, family pedigree, and functional data of the genes critical at various stages of ovarian development to predict women's reproductive life span.

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