Primary and secondary prevention of sudden cardiac death: who should get an ICD?

Santini, Massimo; Lavalle, Carlo; Ricci, Renato Pietro

doi:10.1136/hrt.2006.095190

Cited by 23 publications

(12 citation statements)

References 22 publications

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“…There was a significant association among the younger population (<65 years) on the day of death for AMI and CACD, which are common causes of sudden cardiac death. 38,39 It is assumed that elderly are more sedentary and likely to stay in a hospital or nursing home in the time preceding death. Because most of these facilities in Japan are considered to be equipped with an air-conditioning system, 40 the inmates might have had less exposure to outside air.…”

Section: Discussionmentioning

confidence: 99%

Effects of Fine Particulate Matter on Daily Mortality for Specific Heart Diseases in Japan

Ueda

Nitta

Ono

2009

Circ J

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Section: Discussionmentioning

confidence: 99%

Effects of Fine Particulate Matter on Daily Mortality for Specific Heart Diseases in Japan

Ueda

Nitta

Ono

2009

Circ J

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“…There is, however, a need for more long‐term follow‐up data to assess the risk of recurring VA and the necessity of ICD implantation for secondary prevention purposes in this specific patient category. Patients with a secondary prevention ICD have a higher rate of appropriate ICD therapy as compared to primary prevention 7–9 . However, it is not known whether this also applies to patients with both a transient or correctable cause of the VA as well as a myocardial scar as a substrate.…”

Section: Introductionmentioning

confidence: 99%

ICD implantation for secondary prevention in patients with ventricular arrhythmia in the setting of acute cardiac ischemia and a history of myocardial infarction

Dijk

Quast

Schaap

et al. 2020

Cardiovasc electrophysiol

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Introduction:In patients with a prior myocardial infarction (MI) but preserved left ventricular (LV) function, sustained ventricular arrhythmias (VAs) may arise in the setting of an acute coronary syndrome (ACS). It is unknown whether an implantable cardioverter-defibrillator (ICD) is mandatory in these patients as VA might be triggered by a reversible cause. The purpose of this study is to analyze the benefit of ICD therapy in this patient population. Methods:We conducted a retrospective observational study in ICD recipients implanted from 2008 to 2011. The study group consisted of patients with sustained VA in the setting of an ACS, with a history of MI, but with left ventricular ejection fraction (LVEF) greater than 35 (group A). The two control groups consisted of patients admitted with VA with a history of MI, but without ACS at presentation, either with LVEF greater than 35% (group B) or ≤35% (group C). The primary endpoint was the number of patients with appropriate ICD therapy (antitachycardia pacing or shock).Results: A total of 291 patients were included with a mean follow-up of 5.3 years.Appropriate ICD therapy occurred in 45.6% of the patients in group A vs 51.6% and 60.4% in groups B and C (P = .11). In group A, 31.1% received an appropriate ICD shock vs 34.7% and 44.3% in control groups B and C (P = .12).Conclusion: On the basis of these data, ICD implantation seems warranted in patients with history of MI presenting with VA in the setting of an ACS, despite preserved LV function and adequate revascularization. Further trials, preferably randomizes, should be performed to address these findings. K E Y W O R D Sacute coronary syndrome, ICD, secondary prevention, ventricular arrhythmia

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“…Sudden cardiac death (SCD) is associated with excess mortality in patients affected by congestive heart failure (CHF) due to ischemic or nonischemic cardiomyopathy. 1 Various trials have refuted the hypothesis that antiarrhythmic drugs are useful to improve survival in patients with systolic dysfunction and implantable cardioverter defibrillators (ICD) are actually employed in the primary prevention of SCD in heart failure patients. Left ventricular ejection fraction (LVEF), alone or in combination with other indicators, is considered the main predictor of arrhythmic death in CHF patients.…”

Section: Introductionmentioning

confidence: 99%

“…Left ventricular ejection fraction (LVEF), alone or in combination with other indicators, is considered the main predictor of arrhythmic death in CHF patients. 1 It has been recognized that patients with cardiac dysfunction frequently have undiagnosed sleep disordered breathing (SDB). 2 A recent analysis of postinfarction nondiabetic patients with systolic heart failure has shown that individuals with a body mass index (BMI) > 30 kg/m 2 have a significantly higher risk of appropriate ICD shock therapy.…”

Section: Introductionmentioning

confidence: 99%

Sleep Disordered Breathing is Associated with Appropriate Implantable Cardioverter Defibrillator Therapy in Congestive Heart Failure Patients

Tomaello

Zanolla

Vassanelli

et al. 2010

Clinical Cardiology

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Background: Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population. Hypothesis: To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients. Methods: A total of 22 consecutive ICD patients with systolic CHF (left ventricular ejection fraction [LVEF]<45%) were studied by polysomnography. Results: A total of 17 (77.2%) showed SDB (apnea-hypopnea index [AHI] 10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges (r = 0.718; P < .001, r = −0.619; P = .003, respectively). Conclusions: Sleep disordered breathing is frequent in ICD recipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges.

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Primary and secondary prevention of sudden cardiac death: who should get an ICD?

Cited by 23 publications

References 22 publications

Effects of Fine Particulate Matter on Daily Mortality for Specific Heart Diseases in Japan

Effects of Fine Particulate Matter on Daily Mortality for Specific Heart Diseases in Japan

ICD implantation for secondary prevention in patients with ventricular arrhythmia in the setting of acute cardiac ischemia and a history of myocardial infarction

Sleep Disordered Breathing is Associated with Appropriate Implantable Cardioverter Defibrillator Therapy in Congestive Heart Failure Patients

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