Primary aortic thrombosis: role of enhanced multislice CT demonstrated in three exceptional cases.

Verbeeck, N; Cavez, N; Plawny, Laurent; Weber, Jean-Marie; Lens, V.

doi:10.5334/jbr-btr.39

Cited by 12 publications

(10 citation statements)

References 2 publications

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“…Chemotherapy, illicit drug use, thrombocythemia, heparin-induced thrombocytopenia, and acute pancreatitis are some of the other conditions where primary aortic thrombosis may be associated. 1 This condition has been described in the peripheral arteries of the upper and lower extremities and a few authenticated reports of the same affecting the aorta 2 .…”

Section: Discussionmentioning

confidence: 92%

Hybrid technique for the management of thoracoabdominal aortic thrombosis and symptomatic Trans-Atlantic Inter-Society Consensus “C” aorto-iliac disease

Khan

Vasudevan

2017

Vascular

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Objective Thrombotic disease of the thoracic and abdominal aorta co-existing with aorto-iliac disease is a rare clinical association, which poses a great therapeutic challenge and adds to the complexity of the open surgical repair. Method We describe a case of 53-year-old woman with symptomatic thrombus in the thoracic and abdominal aorta down to the aortic bifurcation, which was successfully treated by Thoracic EndoVascular Aortic Repair via the left subclavian artery, open thrombectomy and aorto-iliac bypass. Result Completion angiogram performed through the axillary cannula showed good flow in the aorta, visceral vessels and iliac arteries. Conclusion This hybrid technical approach was a safe and effective strategy to tackle diffuse aortic thrombus with minimal morbidity and visceral embolization. Simultaneous aorto bi iliac bypass with thoracic endovascular aortic repair is a viable approach that can be undertaken with lesser morbidity and mortality risk as compared to complex and highly stressful total open surgical repair.

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Section: Discussionmentioning

confidence: 92%

Hybrid technique for the management of thoracoabdominal aortic thrombosis and symptomatic Trans-Atlantic Inter-Society Consensus “C” aorto-iliac disease

Khan

Vasudevan

2017

Vascular

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“…Arterial thrombus formation, however, is very uncommon, and aortic involvement is extremely rare. In a review of the literature, we were only able to find 3 cases of aortic mural thrombi formation secondary to acute pancreatitis, all of which involved the retropancreatic aorta [ 2 , 3 ]. To our knowledge, this is the first report in the literature describing thrombi in the ascending aorta.…”

Section: Discussionmentioning

confidence: 99%

“…Primary aortic thrombosis is defined as the development of thrombosis without underlying atheromatous lesions in the aorta [ 2 ]. The etiologies of primary aortic thrombosis are diverse, ranging from chemotherapy to treat cancer to heparin-induced thrombocytopenia and inflammatory bowel disease [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Multiple Ascending Aortic Mural Thrombi and Acute Necrotizing Mediastinitis Secondary to Acute Pancreatitis

Chong

Yun

Kim

et al. 2016

Korean J Thorac Cardiovasc Surg

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The formation of aortic thrombi is an extremely rare complication of acute pancreatitis. Here we report a case of acute pancreatitis complicated by a paraesophageal pseudocyst, necrotizing mediastinitis, and the formation of multiple thrombi in the ascending aorta. The patient was successfully treated by surgical therapy, which included extensive debridement of the mediastinum and removal of the aortic thrombi under cardiopulmonary bypass. Although esophageal resection was not carried out concomitantly, the lesions were resolved and the patient remained free of complications over 2 years of follow-up care.

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“… 1 It could be secondary to syphilitic aortitis, extrinsic pressure by tumors, pelvic peritonitis, irradiation to the abdomen, inflammatory diseases of the digestive tract, and acute episodes of pancreatitis. 2 Systemic conditions lead to hypercoagulable states such as cancer chemotherapy, cocaine intake, and essential thrombocythemia.…”

Section: Short Communicationmentioning

confidence: 99%

“…Intravenous contrast-enhanced multislice CT is the imaging modality of choice to investigate the disorder as it is widely available, noninvasive, and relatively cheap and can identify the extension of the thrombi and complications. 2 …”

Section: Short Communicationmentioning

confidence: 99%

Resolution of Primary Aortic Thrombosis after Dabigatran therapy—A New Hope for the Rare and Old Disease

Jariwala

Kale

2019

Indian Heart Journal

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The primary aortic thrombosis (PAT) is an uncommon noncardiac cause of distal peripheral embolization to lower extremities. Also, this condition develops in the absence of extensive atherosclerosis of aorta or abnormal dilatation like aneurysm of the aorta. In most of the cases, there was either no or minimal atherosclerosis of the aorta. The disease can involve any part of the aorta, but in most of the cases, the thoracic aorta below the origin of the left subclavian artery followed by the infrarenal portion of the abdominal aorta was the most common site of involvement. In our case, there was extensive thrombosis starting from the lower part of the thoracic aorta extending across both the renal arteries up to the aortic bifurcation without any underlying aortic pathology or hypercoagulable disease. There are no guidelines for the management of the PAT, but our experience is based on few case series, case reports, and meta-analysis where there are variable success rate using conservative medical management, endovascular procedure, or surgical thrombectomy. Vitamin K antagonist was the drug of choice in all the cases as a part of conservative medical management or used to prevent recurrence after the endovascular or surgical procedure. We present a case of PAT where the use of dabigatran leads to complete resolution and prevented the recurrence of the disease during two-year follow-up, which is the first and unique case report of the literature.

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Primary aortic thrombosis: role of enhanced multislice CT demonstrated in three exceptional cases.

Cited by 12 publications

References 2 publications

Hybrid technique for the management of thoracoabdominal aortic thrombosis and symptomatic Trans-Atlantic Inter-Society Consensus “C” aorto-iliac disease

Hybrid technique for the management of thoracoabdominal aortic thrombosis and symptomatic Trans-Atlantic Inter-Society Consensus “C” aorto-iliac disease

Multiple Ascending Aortic Mural Thrombi and Acute Necrotizing Mediastinitis Secondary to Acute Pancreatitis

Resolution of Primary Aortic Thrombosis after Dabigatran therapy—A New Hope for the Rare and Old Disease

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