Primary Carcinoma of the Seminal Vesicle

Dalgaard, Jørgen B.; Giertsen, J. Chr.

doi:10.1111/j.1699-0463.1956.tb03400.x

Cited by 68 publications

(29 citation statements)

References 5 publications

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“…Daalgard and Giertsen have proposed diagnostic criteria to identify primary tumours of the seminal vesicles 10. The tumour should be a macroscopically and microscopically verified carcinoma, localised exclusively or mainly to the seminal vesicle; there must be no other primary carcinoma elsewhere in the body; and the tumour should preferably be a papillary adenocarcinoma resembling the architecture of the non-neoplastic seminal vesicle.…”

Section: Discussionmentioning

confidence: 99%

Metastatic primary seminal vesicle adenocarcinoma: management of a rare tumour with multiagent chemotherapy and hormonal therapy

et al. 2017

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Primary seminal vesicle adenocarcinoma is one of the rarest genitourinary cancers. The pathogenesis is unknown and clinical manifestations are protean. There is no defined treatment for this disease and various combinations of surgery, chemotherapy, radiation therapy and hormonal therapy have been used in the past. Here, we have reported a primary seminal vesicle adenocarcinoma with hepatic metastases, managed with multiagent chemotherapy (oxaliplatin and 5-fluorouracil based) and androgen ablation (with triptorelin). The key to management of such a case is early diagnosis and multimodal treatment. The reported survival rate continues to be poor even for a localised disease. A consolidated follow-up protocol ensures early diagnosis of recurrent or metastatic disease so that second-line therapy can be started.

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Section: Discussionmentioning

confidence: 99%

Metastatic primary seminal vesicle adenocarcinoma: management of a rare tumour with multiagent chemotherapy and hormonal therapy

et al. 2017

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“…Because involvement of seminal vesicle by prostatic adenocarcinoma is a common occurrence (approximately in 12% of patients with clinically low stage prostate cancer on pathologic evaluation of their prostatectomy specimen), since 1956 Dalgaard and Giertsen applied strict criteria to diagnose primary neoplasms: the lesion must be a papillary or anaplastic carcinoma that is primarily localized in the seminal vesicle in absence of other primary carcinoma in the region (specifically, prostate or colorectal carcinoma) [1]. If a tumor large size prevents the accurate determination of the site of origin, seminal vesicle is distinguished from prostatic neoplasms by the absence of prostate specific antigen (PSA) staining [2].…”

Section: Discussionmentioning

confidence: 99%

Cystosarcoma Phyllodes of the Seminal Vesicle: A Case Report and Literature Review

Olivetti

Laffranchi

Luca

2014

Case Reports in Urology

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Cystosarcoma of the seminal vesicle is a very rare malignant tumor; in the literature only four cases are reported. We present a case of cystosarcoma phyllodes arising in the right seminal vesicle of a 49-year-old man without any urinary symptom but with persistent constipation. Ultrasound examination showed a mass at the right superior base of the prostate subsequently studied with CT and MRI. The patient underwent vesiculectomy; his postoperative course was uneventful. The patient is still well, without evidence of recurrent disease.

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“…The prostatic zones differ in their respective cancer susceptibility; the inner zone is the most common site of BPH while the outer zone is the most likely site of PCs. Differences in developmental patterns between the prostate and adjacent accessory glands may be responsible for the profound differences in their cancer susceptibility, as only about 50 cases of seminal vesicle adenocarcinoma have been reported [103]. Most prostate tumors are dependent on circulating androgens for growth and, accordingly, early interventions are aimed at lowering serum androgen levels [104].…”

Section: 00 Edcs In Prostatic Development and Cancermentioning

confidence: 99%

Environmental endocrine disruptors: Effects on the human male reproductive system

Sweeney

Hasan

Soto

et al. 2015

Rev Endocr Metab Disord

142

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Incidences of altered development and neoplasia of male reproductive organs have increased during the last 50 years, as shown by epidemiological data. These data are associated with the increased presence of environmental chemicals, specifically “endocrine disruptors,” that interfere with normal hormonal action. Much research has gone into testing the effects of specific endocrine disrupting chemicals (EDCs) on the development of male reproductive organs and endocrine-related cancers in both in vitro and in vivo models. Efforts have been made to bridge the accruing laboratory findings with the epidemiological data to draw conclusions regarding the relationship between EDCs, altered development and carcinogenesis. The ability of EDCs to predispose target fetal and adult tissues to neoplastic transformation is best explained under the framework of the tissue organization field theory of carcinogenesis (TOFT), which posits that carcinogenesis is development gone awry. Here, we focus on the available evidence, from both empirical and epidemiological studies, regarding the effects of EDCs on male reproductive development and carcinogenesis of endocrine target tissues. We also critique current research methodology utilized in the investigation of EDCs effects and outline what could possibly be done to address these obstacles moving forward.

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Primary Carcinoma of the Seminal Vesicle

Cited by 68 publications

References 5 publications

Metastatic primary seminal vesicle adenocarcinoma: management of a rare tumour with multiagent chemotherapy and hormonal therapy

Metastatic primary seminal vesicle adenocarcinoma: management of a rare tumour with multiagent chemotherapy and hormonal therapy

Cystosarcoma Phyllodes of the Seminal Vesicle: A Case Report and Literature Review

Environmental endocrine disruptors: Effects on the human male reproductive system

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