Primary Cardiac Angiosarcoma Associated With Cardiac Tamponade

Oshima, Kiyohiro; Ohtaki, Akio; Kano, Motoi; Tange, Syouiti; Ikeda, Fumihiro; Ishikawa, Susumu; Morishita, Yasuo

doi:10.1253/jcj.63.822

Cited by 24 publications

(23 citation statements)

References 9 publications

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“…In a case series of 366 cases, 3% of the tumors originated from the heart or great vessels, or both. Angiosarcoma of the heart involves almost exclusively the right atrium, but has already been reported in other cardiac chambers 5,6 . The symptoms resulting from primary tumors of the heart are usually late and more related to their location than to their histological type, which makes the early diagnosis difficult, impairing the efficacy of treatment.…”

Section: Discussionmentioning

confidence: 96%

“…They are often associated with pericardial effusion and cardiac tamponade. Myocardial rupture due to tumoral infiltration and necrosis of the wall may occur, multiseptate hemopericardium being the most frequent echocardiographic finding in the few cases reported 2,6 . The symptoms resulting from mechanical cardiac impairment are usually preceded by malaise, fever, weight loss, fatigue, and anemia that occur weeks or months before symptom onset.…”

Section: Discussionmentioning

confidence: 99%

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Spontaneous rupture of a right atrial angiosarcoma and cardiac tamponade

Corso¹,

Kraychete²,

Nardeli³

et al. 2003

Arq. Bras. Cardiol.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Spontaneous rupture of a right atrial angiosarcoma and cardiac tamponade

Corso¹,

Kraychete²,

Nardeli³

et al. 2003

Arq. Bras. Cardiol.

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“…[4] Frequently, patients present with symptoms of pericardial effusion or tamponade because as the tumor rapidly grows into the myocardium, it tends to bleed. [6,7] When pericardiocentesis is performed, cytologic examination is often negative. [4,8,9] PCAs are highly aggressive tumors, with approximately 66% to 89% metastatic at diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Nausea and vomiting masquerading heart cancer

Shapiro

Vasile

Klarich

et al. 2016

JST

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Primary cardiac tumors are extremely rare, although only 20% are malignant. Of the malignant tumors, sarcomas are the most common type and usually present with signs and symptoms of pericardial effusion or tamponade, including dyspnea, chest pain, or syncope. We present the case of a woman with nausea, vomiting, and epigastric pain who eventually received the diagnosis of a large cardiac angiosarcoma. To our knowledge, no case reports have described patients with primary cardiac tumors presenting with nausea and vomiting without cardiac symptoms. Our patient was treated with open heart resection of the tumor and reconstruction of the right atrium with bovine pericardium. This case highlights an atypical presentation of this rare condition and shows the current optimal management.

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“…Outcomes associated with these tumors are very poor due to their aggressive character and due to late diagnosis, with 80% of patients already presenting with metastases at the time of diagnosis [2]. Surgical resection of primary tumor should be attempted when feasible, as overall survival (OS) may be improved.…”

Section: Discussionmentioning

confidence: 99%

A case of pericardial angiosarcoma with refractory pericardial tamponade treated with multidisciplinary therapy with pericardial fenestration, radiotherapy and chemotherapy

Hirano¹,

Kyoko²,

Ichinose³

et al. 2015

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. Case Report: This report describes a case of a 50-year-old male with pericardial angiosarcoma presenting with cardiac tamponade. Repeat pericardiocentesis showed bloody fluid with cytopathology negative for malignant cells. Pericardial fenestration was performed to prevent recurrent pericardial tamponade due to poor drainage. A diagnosis of cardiac angiosarcoma was made based on the resected pericardium and a biopsied specimen from gluteus medius muscle. The patient responded to combination therapy with docetaxel and radiotherapy. However, the patient died four months after diagnosis due to intraperitoneal bleeding from liver metastases. The patient was not dependent on a chest tube or a pericardial drain before he died. At autopsy, only a small amount of residual tumor was revealed around the heart. Conclusion: There is a possibility that palliative local control against refractory cardiac tamponade could be obtained via multidisciplinary therapy with pericardial fenestration, radiotherapy, and chemotherapy. IJCRI publishes

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Primary Cardiac Angiosarcoma Associated With Cardiac Tamponade

Cited by 24 publications

References 9 publications

Spontaneous rupture of a right atrial angiosarcoma and cardiac tamponade

Spontaneous rupture of a right atrial angiosarcoma and cardiac tamponade

Nausea and vomiting masquerading heart cancer

A case of pericardial angiosarcoma with refractory pericardial tamponade treated with multidisciplinary therapy with pericardial fenestration, radiotherapy and chemotherapy

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