Primary Cardiac Leiomyoma of the Ventricular Septum: A Rare Form of Pediatric Intracardiac Tumor

Melo, Isabel S.; Belo, Filipa; Gouveia, Rosa; Anjos, Rui

doi:10.1007/s00246-012-0161-7

Cited by 13 publications

(11 citation statements)

References 5 publications

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“…Two cases of cardiac leiomyomas in boys demonstrated the existence of primary forms of cardiac leiomyoma [5,6]. The pathologic finding of a direct connection of the tumor with the tunica media of the intramyocardial vessel in our patient is similar to the report mentioned earlier [6].…”

Section: Commentsupporting

confidence: 90%

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Multiple Primary Leiomyomas in the Right Ventricle: A Rare Form of Leiomyoma

Zhu

et al. 2016

The Annals of Thoracic Surgery

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A case of multiple benign leiomyomas in the right ventricle of a 47-year-old woman is presented. Multiple lesions were revealed at different locations in the right ventricle; 1 lesion extended into the right pulmonary artery. Histologic examination showed benign leiomyomas arising from the tunica media of the intramyocardial vessels. Also, the primary origin of the cardiac tumors is demonstrated by the evidence that no leiomyoma was found in the genital system 30 months after the cardiac operation. To our knowledge, this is the first case report of multiple primary cardiac leiomyomas in a premenopausal woman. The midterm prognosis after complete resection is good.

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Section: Commentsupporting

confidence: 90%

“…There are only 3 female and 2 male cases reported in the English literature. The origins of the first 2 female cases [2][3] were identified as metastases, and the third female case [4] and 2 male cases [5][6] were identified as primary lesions.…”

Section: Commentmentioning

confidence: 99%

Multiple Primary Leiomyomas in the Right Ventricle: A Rare Form of Leiomyoma

Zhu

et al. 2016

The Annals of Thoracic Surgery

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“…Primary leiomyomas of the heart are extremely rare. Those which occur are a result of cardiac extensions of intravenous leiomyomatosis through the inferior vena cava (Melo et al 2012). Others result from metastatic benign leiomyoma (MBL) and also from venous seeding following hysterectomy in case of women patients (Consamus et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Primary leiomyoma of the left ventricle leading to sudden and unexpected death in a 74-year-old male: a case report

Yahaya

2020

Egypt J Forensic Sci

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Background Primary cardiac tumours arising from smooth muscle cells are said to be very rare in the literature. Primary leiomyoma of the heart particularly in men is extremely rare. To the best of my knowledge, there are only two reported cases of boys with primary leiomyoma of the heart in the English literature. Most of leiomyoma tumours involving the heart reported in the literature are a result of cardiac extensions of intravenous leiomyomatosis through the inferior vena cava. Case presentation A case of left ventricular primary leiomyoma in a 74-year-old male is reported. He had no known previous history of heart disease but he died suddenly and unexpectedly. At autopsy, the heart measured 420 gm and when it was opened, a solid tumour of size 4 × 3 × 2 cm involving the lower left ventricle on the anterior aspect of the heart was found. The tumour was extending to the left ventricular septum and was growing by protruding into the left ventricle chamber which finally was confirmed histopathologically to be a leiomyoma. Conclusion Cardiac benign tumours are rare and can be life threatening because of embolization following their detachment which is manifested clinically by stroke. Additionally, they are clinically asymptomatic; therefore, they cannot be easily detected. In case of clinical suspicion, echocardiography and other imaging diagnostic tests should be used to confirm presence of a tumour.

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“…Primary cardiac leiomyoma has been described in three cases. In these cases the neoplasia originated from the right ventricle wall, creating a right ventricular outflow obstruction [6,7], or extensively involving the ventricular septum [8]. In our patient, symptoms (dyspnea, palpitation, and syncope) were related to severe right outflow obstruction and tricuspid regurgitation caused by the mass.…”

Section: Commentmentioning

confidence: 78%

Primary Cardiac Leiomyoma Causing Right Ventricular Obstruction and Tricuspid Regurgitation

Careddu

Foà

Leone

et al. 2017

The Annals of Thoracic Surgery

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We report the unique case of a primary cardiac leiomyoma originating from the right ventricle and involving the tricuspid valve in a 43-year-old woman. Echocardiography showed a giant mass causing severe pulmonary stenosis and tricuspid valve regurgitation. The patient underwent surgical excision and histologic examination revealed a primary cardiac leiomyoma. To the best of our knowledge only three cases of primary cardiac leiomyoma have so far been reported, and this is the first case of primary cardiac leiomyoma involving the tricuspid valve apparatus.

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Primary Cardiac Leiomyoma of the Ventricular Septum: A Rare Form of Pediatric Intracardiac Tumor

Cited by 13 publications

References 5 publications

Multiple Primary Leiomyomas in the Right Ventricle: A Rare Form of Leiomyoma

Multiple Primary Leiomyomas in the Right Ventricle: A Rare Form of Leiomyoma

Primary leiomyoma of the left ventricle leading to sudden and unexpected death in a 74-year-old male: a case report

Primary Cardiac Leiomyoma Causing Right Ventricular Obstruction and Tricuspid Regurgitation

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