“…Seven were randomized controlled trials, 9,21,23,24,38,42,43 and the other 19 were retrospective cohort studies or prospective cohort studies. Sixteen studies 9,12,21,23,26,28,30,33,34,37–41,43,44 compared LCBDE+PDC with LCBDE+TTD. Eight studies 24,25,28,29,32,36,42,45 compared LCBDE+PDC+IBD with LCBDE+TTD; three studies 27,31,35 compared LCBDE+ PDC+EBD with LCBDE+TTD; and one study 28 compared three bile duct closure methods following LCBDE ( Table 1 ).…”