Primary Corneal Squamous Cell Carcinoma in a Dog: Clinical and Histopathological Evaluation

Barsotti, Giovanni; Ressel, Lorenzo; Finotello, Riccardo; Marchetti, Veronica; Millanta, Francesca

doi:10.1155/2012/596593

Cited by 4 publications

(4 citation statements)

References 35 publications

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“…A report by [12] stated that neoplastic cells of adenocarcinoma were round to polygonal, pleomorphic with abundant cytoplasm, with irregularly shaped immature nuclei characterized by a high grade anisokaryosis and multiple nucleoli. Additionally [8] also reported that the cells of adenocarcinoma were basophilic, columnar and cuboidal with basal, prominent, hyperchromatic, condensed nuclei and moderate amount of cytoplasm.…”

Section: Resultsmentioning

confidence: 99%

Case Report Of Adenocarcinoma On Palpebral Of Rotweiler Dog: A Histopathological Evaluation

et al. 2020

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Eyelid neoplasms cases are the most frequently recorded ophthalmic tumors in dogs, which mostly benign and only few are reported as being malignant. Adenocarcinoma is one of malignant tumor reported in dog eyes beside fibrosarcoma, squamous cell carcinoma, and hemangiosarcoma. A case of adenocarcinoma in palpebral of a 6-year-old male rotweiller dog with 6month history of a progressive mass on the left eye was presented. Pathological examination showed a severe exophytic irregular pink to red cauliflower-like mass occupying all surface of the eye lid. A transpalpebral enucleation was performed to collect the mass, followed by histopathological slide preparation using Hematoxylin-Eosin (HE) staining. Histopathological examination showed various sizes lobules separated by connective tissue. Many angioneogenesis figure were also observed. The irregular arranged of anaplastic cells was obviously seen with hyperchromatic and pleomorphic of the nuclei and various shapes and sizes of cell structures as well. There was no sign of encapsulated area, however, few mitotic figures were seen. The histopathological examination result confirmed the presence of adenocarcinoma.

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Section: Resultsmentioning

confidence: 99%

Case Report Of Adenocarcinoma On Palpebral Of Rotweiler Dog: A Histopathological Evaluation

et al. 2020

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“…Slides prepared from a canine renal macula densa tissue and a squamous cell carcinoma known to express COX‐2 served as positive controls. Evaluation of COX‐2 expression was quantified by a previously described scoring system based on estimation of the percentage of immunoreactive cells combined with an estimation of the staining intensity . The scoring system was as follows: 0, no staining; +1, weak diffuse cytoplasmic staining (may contain stronger intensity in <10% of the cells); +2, moderate to strong granular cytoplasmic staining in 10–90% of the cells; and +3, >90% of the cells stained with strong intensity.…”

Section: Methodsmentioning

confidence: 99%

Clinical outcome and cyclo‐oxygenase‐2 expression in five dogs with solar dermatitis/actinic keratosis treated with firocoxib

Albanese¹,

Abramo

Caporali³

et al. 2013

Veterinary Dermatology

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“…Two cases (0.04%), had been suferred of transitory serosanguineous or bloody unilateral nasal discharge in week following enucleation which disappeared spontaneously in a short period. Ascientific paper in dogs (20), had been reported minor bloody discharge from the nostril on the same side of the surgery in one dog.This sign resolved within 48hrs., without any treatment.…”

Section: Figure-8 Histopathological Section Show's Neoplastic Cells W...mentioning

confidence: 96%

A Survey and Treatment of Ocular Carcinomas in Iraqi Dairy Cows from (1987- 2012)

Al-Asadi

2012

Kufa Jou. Vete. Med. Sci.

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The purpose of this study was to survey and describe the Iraqi dairy cows population underwent eye enucleation, referring to possible complications that may be happened, the type and pathomorphological features of ocular neoplastic growths. During a study period of (25) years. A total of (12000), cows were examined. Of these 500 cows (4.17%) of different ages (3 to 12) years sufer from ocular tumors. Some of these cows were in various pregnancy stages. All animals under investigation were (local and cross breed) and from five dairy farms around Baghdad province.The majority of the cases 174 (34.8%) observed in Alrathwanya. The mostly affected age ranged between (7-8) years, the number reached 185 (37%). According to the seasons of the year, summer recored the highest number of affections, 260 (52%).The Lesions were present in the right eye 256 cases (51.2% ), in the left eye 244 cases (48.8%). Their were significant differences between non-pregnant, 425 (85%) and pregnant cows, 75 (15%). Using standard procedures, the tumors were excised surgically under the effect of local anesthesia (lidocaine 2%) with or without sedation The major surgical complications were hemorrhage in (7%) of the cases. Sewelling of pre-orbital region were observed in (15%). Orbital infections were noticed in (3%) of the cases. Partial dehiscence of the suture line was happened in (4%) of the treatment cases.Two cases (0.04%), showed transitory serosanguineous or bloody unilateral nasal discharge. Four cases (0.08%) developed recurrent tumors. Only one pregnant cow was aborted. Two cows were culled, two years post-surgery. Finally two cows were died from causes not related to surgery. The removal lesions had a nodular or cauliflower-like appearance and were varied in size from a few centimeters (12 %) to several centimeters (88%). Over a quarter (25%) of tumor lesions were ulcerated and bled easily. Microscopical apperances showed (well differentiated squamous cell carcinoma), characterized by formation of keratin pearls appear as red onion-like structures surround by inflammatory cells infiltration. The neoplastic cells showed mitotic figures, some of these cells have nucleus with prominent nucleoli. In conclusion, eye enucleation will remain an inexpensive, safe and viable treatment option for ocular diseases, in addition it increase the longevity of the cows within the herd.

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Primary Corneal Squamous Cell Carcinoma in a Dog: Clinical and Histopathological Evaluation

Cited by 4 publications

References 35 publications

Case Report Of Adenocarcinoma On Palpebral Of Rotweiler Dog: A Histopathological Evaluation

Case Report Of Adenocarcinoma On Palpebral Of Rotweiler Dog: A Histopathological Evaluation

Clinical outcome and cyclo‐oxygenase‐2 expression in five dogs with solar dermatitis/actinic keratosis treated with firocoxib

A Survey and Treatment of Ocular Carcinomas in Iraqi Dairy Cows from (1987- 2012)

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