Primary Cutaneous Large B-Cell Lymphoma, Leg Type

Thomas, Vibha Taneja; Dobson, Robin; Mennel, Robert G.

doi:10.1080/08998280.2011.11928757

Cited by 20 publications

(20 citation statements)

References 24 publications

(28 reference statements)

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“…El diagnóstico se basa en la clínica, la histología, la inmunohistoquímica y el análisis genotípico en el especímen de la biopsia (2,5). La patología muestra un infiltrado difuso de células B, con ausencia de epidermotropismo y extensión al tejido celular subcutáneo.…”

Section: Discussionunclassified

Linfoma cutáneo primario de células B, del tipo de la pierna

et al. 2012

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ResumenEl linfoma de células B del tipo de la pierna, es una neoplasia rara y agresiva, con características clínicas, morfológicas e inmunofenotípicas distintivas. Está clasificada dentro del grupo de linfomas cutáneos primarios de células B y se presenta en edades avanzadas, con predominio en mujeres y altas tasas de recurrencia. Presentamos el caso de una mujer de 63 años de edad, con diagnóstico clínico e inmunofenotípico de linfoma cutáneo de células B del tipo de la pierna.Palabras clave: linfoma cutáneo primario de células B, tipo de la pierna, inmunofenotipo, Rituximab. PRIMARY CUTANEOUS B CELL LYMPHOMA, LEG TYPE AbstractPrimary cutaneous B−cell lymphoma, leg type, is an uncommon and aggressive neoplasm with unique clinical features, morphology and immunophenotype. It is classified as a primary B−cell cutaneous lymphoma and it occurs in advanced age and women with high rates of recurrences. We present the case of a 63−year−old woman, with clinical and immunophenotypic diagnosis of primary cutaneous B−cell lymphoma, leg type.Key words: Primary cutaneous B−cell lymphoma, leg type, immunophenotype, Rituximab LINFOMA CUTÂNEO PRIMÁRIO DE CÉLULAS B, DO TIPO DA PERNA ResumoO linfoma de células B do tipo da perna é uma neoplasia rara e agressiva, com características clínicas, morfológicas e imunofenotípicas distintivas. Está classificado dentro do grupo de linfomas cutâneos primários de células B e se apresenta em idades avançadas, com predomínio em mulheres e altas taxas de recorrência. Apresentamos o caso de uma mulher de 63 anos de idade, com diagnóstico clínico e inmunofenotípico de linfoma cutâneo de células B do tipo da perna.Palavras chave: Linfoma cutâneo primário de células B, tipo da perna, inmunofenotipo, Rituximab.

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Section: Discussionunclassified

Linfoma cutáneo primario de células B, del tipo de la pierna

et al. 2012

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“…This entity predominantly affects elderly women; clinically, patients present with solitary or multiple, red or violaceous nodules or tumours mostly located on the legs, with a tendency to a rapid growth (6) and possible ulceration. Non-leg localisation of the PCDLBCL LT has also been reported (7) and the tendency to extracutaneous dissemination results in a poor prognosis of this primary cutaneous lymphoma (8).…”

Section: Key Messagesmentioning

confidence: 93%

Cutaneous lymphoma misdiagnosed as chronic lymphadenitis

Munteanu

Mohor

Baderca

et al. 2015

International Wound Journal

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Cutaneous lymphomas (CLs) represent a group of lymphoproliferative disorders that can be difficult to diagnose in the early stage because they could mimic many benign inflammatory dermatoses (chronic eczema, bullous dermatosis, idiopathic erythroderma, psoriasis, lymphadenitis). Primary cutaneous B-cell lymphomas are a unique and controversial group of skin lymphomas characterised by the absence of extracutaneous manifestations at diagnosis. We present the case of a 60-year-old man with 7-month history of a growing inguinal mass/tumour, which was misdiagnosed as inguinal chronic lymphadenitis. Recognition of the correct entity, primary cutaneous diffuse large B-cell lymphoma leg type, led to an appropriate therapeutic strategy, knowing that these types of tumours behave more aggressively than other types of primary cutaneous B-cell lymphomas. The patient was discharged with rituximab + chemotherapy indication and favourable outcome. The aim of the presentation is to describe these common skin manifestations, however seen in a primary cutaneous B-cell lymphoma, which underlines the necessity of rigorous monitoring/long-term follow-up as well as exhaustive histopathological analysis for the diagnosis.

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“…1 However, PCDLBCL-LT may also develop in body sites other than legs in 10% to 20% of cases. 2 Although PCDLBCL-LT remains limited to the skin in most of patients, there may be further involvement of lymph nodes and bone marrow. 1 Here, we would like to present a unique case of PCDLBCL-LT developing on both the upper and lower extremities, as well as having nasal mucosal extension.…”

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confidence: 99%