Primary cutaneous mucormycosis in a premature neonate and its management by tumescent skin grafting

Kumar, Vishal; Aggarwal, Aditya; Taneja, Rashmi; Saha, Shiv Shankar; Khazanchi, Rakesh Kumar; Kler, Neelam; Saluja, Satish

doi:10.1016/j.bjps.2005.01.005

Cited by 14 publications

(5 citation statements)

References 2 publications

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“…[2] included 176 cases (19%) of cutaneous zygomycosis. We searched PubMed for case reports of cutaneous zygomycosis published from 2004 through 2008 in English, selecting only articles describing cases in which the diagnosis had been confirmed by histology and/or culture, and identified 78 cases [3–65]. The large number of publications in recent years may reflect the greater awareness in the part of physicians of this infection, as well as publication bias, but there are also data which support an actual increase in the incidence of zygomycosis, mainly in patients with haematological malignancies [66].…”

Section: Epidemiologymentioning

confidence: 99%

Cutaneous zygomycosis

and¹,

Petrikkos²

2009

Clinical Microbiology and Infection

113

122

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The prevalence of cutaneous and soft tissue zygomycosis appears to have increased in recent years. We reviewed 78 case reports of cutaneous zygomycosis published from 2004 through 2008. Most patients with cutaneous zygomycosis have underlying conditions such as haematological malignancies, diabetes mellitus or solid organ transplantation, but a large proportion of them are immunocompetent. Trauma is the most common predisposing factor leading to zygomycosis in immunocompetent patients. If the patient is immunocompromised, the infection may disseminate. Cutaneous zygomycosis may be localized, may extend to deep underlying tissues, or may be disseminated. The most common clinical presentation is induration of the skin with surrounding erythema, rapidly progressing to necrosis. Histological examination and culture of soft tissue are important for the diagnosis of cutaneous zygomycosis. Treatment consists of surgical debridement, administration of antifungal agents (amphotericin B formulations and/or posaconazole) and, occasionally, hyperbaric oxygen. Mortality rates are approximately 30%.

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Section: Epidemiologymentioning

confidence: 99%

Cutaneous zygomycosis

and¹,

Petrikkos²

2009

Clinical Microbiology and Infection

113

122

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“…Les mucormycoses à Absidia corymbifera, récemment renommé Lichteimia, sont rares en pathologie humaine, elles surviennent sur un terrain d'immunodépression, exceptionnellement chez un immunocompétent [6,9,15].…”

Section: Discussionunclassified

Les mucormycoses sous-cutanées à Lichtheimia corymbifera : à propos d’un cas chez un enfant immunocompétent

Razouk

Sebbani

Agoumi

et al. 2012

Journal de Mycologie Médicale

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“…[2][3][4][5]8 A sticking plaster tape (Elastoplast; Beiersdorf, Hamburg, Germany) had been a frequent culprit and is now pretreated with irradiated cobalt. 3,4,8 Conversely, the gangrenous form is far more aggressive with rapidly progressive ulceration, eschar formation, necrosis, and hematogenous dissemination.…”

Section: Commentmentioning

confidence: 99%

“…The overall survival rate was 45%. 4,5 Only 3 of these cases, all of whom eventually died of disseminated infection, involved the head and neck. [7][8][9] Therefore, to our knowledge, our patient represents the first neonate or infant to survive a cutaneous mucormycosis infection of the head and neck.…”

Section: Commentmentioning

confidence: 99%

Facial Cutaneous Mucormycosis in a Full-term Infant

Dave

Vivero

Roy

2008

Arch Otolaryngol Head Neck Surg

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Mucormycosis is a rare and potentially fatal fungal infection that most commonly affects the immunocompromised population. Although originally described by Paltauf in 1885 (D. G. Finn as cited by Vessely et al(1)((p573)) and A. M. Marchevsky as cited by Oh and Notrica(2)((p1607))), it was not until 1955 that Harris (as cited by Vessely et al(1)((p573))) reported the first case of a mucormycosis survivor. In recent years, the number of immunosuppressed patients has increased partly owing to the widespread implementation of organ transplantation and the increasing prevalence of human immunodeficiency virus infection. Consequently, the incidence of mucormycosis has also increased, especially in pediatric patients. In the setting of immunocompromise, a high index of suspicion is required to accurately diagnose and treat this potentially lethal infection in a timely fashion. To our knowledge, we report the first case of facial cutaneous mucormycosis in an infant, who also represents the first reported neonate or infant to survive a cutaneous mucormycosis infection of the head and neck.

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Primary cutaneous mucormycosis in a premature neonate and its management by tumescent skin grafting

Cited by 14 publications

References 2 publications

Cutaneous zygomycosis

Cutaneous zygomycosis

Les mucormycoses sous-cutanées à Lichtheimia corymbifera : à propos d’un cas chez un enfant immunocompétent

Facial Cutaneous Mucormycosis in a Full-term Infant

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