Primary Diffuse Large B-cell Lymphoma of the Sigmoid Colon

Haddad, Ibrahim; Kurdi, Bara El; Iskandarani, Mahmoud El; Babar, Sumbal; Young, Mark

doi:10.7759/cureus.5048

Cited by 11 publications

(12 citation statements)

References 8 publications

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“…The most common symptoms were bowel obstruction and abdominal pain that were present in 40% of all 15 cases. In three patients representing nearly 16% of the patient population during the application time, there was perforation (16). In our series, the mean age was estimated at 50 years, which is smaller than that in a previously conducted study in the literature.…”

Section: Discussioncontrasting

confidence: 67%

Comparison of rarely seen tumors of the colorectal region clinicopathologically

Akyüz

Topal

Kültüroğlu

et al. 2021

ircmj

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Background: Majority of colorectal neoplasms are adenocarcinomas but there is a small percentage of tumors from other histological cell lines Method: One thousand one hundred patients who were applied surgical treatment due to colorectal cancer at general surgical clinic between years of 2010-2020 were examined. Patients have been grouped as Diffuse large b cell lymphoma (DLBCL) (group1), Malignant melanoma (group2), Medullary carcinoma (group3), Neuroendocrine tumor (group4) and they were included in the study in this way. In the groups,clinicopathological data of patients and their survival periods have been compared. Results: Twenty patients are included in our study: Group 1 was composed of 5, Group 2 was composed of 4, Group 3 was composed of 3, and Group 4 was composed of 8 patients. Emergency application rate (60%) was higher in Group 1 (p: 0.004). A verage age was above 50 in 4 groups and there was no difference between groups (p:0,966).Tumor diameter was on average (cm)(8 vs 6,55 vs 5,4 vs 3,75 p:0,073) in the groups, The number of lymph nodes dissected were (13 vs 14.5 vs 19 vs 19 p:0.373) The number of metastatic lymph nodes were ( 0 vs 1.5 vs 0 vs 0.5 p:0.188). Survival was significantly shorter in the malignant melanoma group, the longest survival was in the neuroendocrine tumor group (15.625vs8.5vs20 vs 40.857 p:0.001) Conclusions: Although clinicopathological features and postoperative follow-up results were similar, there were differences in survival among patients. Maligant melanoma histopathological type had a worse prognosis than other tumors

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Section: Discussioncontrasting

confidence: 67%

Comparison of rarely seen tumors of the colorectal region clinicopathologically

Akyüz

Topal

Kültüroğlu

et al. 2021

ircmj

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“…CT scan, MRI, and/or PET-CT play an important role in determining the extension of the disease and help in staging the disease [8] . Patients presenting with neurological symptoms may require brain imaging including CT scan, MRI, or lumbar puncture [9] . Depending on the severity and stage of the disease, some patients may require a bone marrow biopsy to rule out an extension to the bone marrow and differentiate between primary and secondary lymphoma.…”

Section: Discussionmentioning

confidence: 99%

A rare case of diffuse large B-cell lymphoma presenting as a malignant mass in both duodenum and ascending colon

Battah

Abed

Shamoon

et al. 2022

Radiology Case Reports

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“…Treatment modalities include chemoradiotherapy; however, the role of surgery in the treatment of DLBCL is still controversial. Some authors believe surgery should be limited to obstruction, perforation, and hemorrhage, while others believe it should be an initial treatment modality [2,3].…”

Section: Introductionmentioning

confidence: 99%

Diffuse Large B-Cell Lymphoma of the Colon in an Asymptomatic Patient

Bandaru¹,

Busa²,

Juneja³

2022

Cureus

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Extranodal lymphomas of the gastrointestinal (GI) tract are known entities, but primary lymphoma of the colon is extremely rare. Symptoms are non-specific, such as abdominal pain, bloody diarrhea, unintentional weight loss, night sweats, and changes in bowel habits. Some patients do not have any specific symptoms, which makes diagnosis extremely difficult. We present a 69-year-old asymptomatic male who was incidentally found to have an inflammatory mass in the descending colon on screening colonoscopy; the initial biopsy was inconclusive. However, due to high suspicion of any underlying malignancy, a repeat colonoscopy with biopsy was done, which revealed diffuse large B-cell lymphoma (DLBCL). Prompt and early diagnosis is extremely crucial for timely management. Management includes chemotherapy, radiotherapy, and surgery.

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Primary Diffuse Large B-cell Lymphoma of the Sigmoid Colon

Cited by 11 publications

References 8 publications

Comparison of rarely seen tumors of the colorectal region clinicopathologically

Comparison of rarely seen tumors of the colorectal region clinicopathologically

A rare case of diffuse large B-cell lymphoma presenting as a malignant mass in both duodenum and ascending colon

Diffuse Large B-Cell Lymphoma of the Colon in an Asymptomatic Patient

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