Primary Embryonal Lung Carcinoma and Testicular Seminoma in the Same Patient Ten-Years Later: Case-Report and Literature Review

Abstract

Primary germ cell tumors of lung are extremely rare. The prognosis is usually poor, with various symptoms seriously affecting quality of life. In this paper we describe the unique case of a patient affected by an embryonal carcinoma of lung and a testicular seminoma after ten years. We also report literature about pulmonary extragonadal germ cell tumors

Pure embryonal carcinoma of the testis in an adult male patient: case report

“…The main reason for embryonal carcinoma's aggressiveness is the tendency of early hematogenous invasion [3]. The median survival time was 5 months and 1, 2 and 5 year survival rates of 41%, 34% and 34%, respectively [7].The case was a 36-year-old male, who applied to the clinic with complaints of pain and swelling in the left testis and chilling-shivering. In the physical examination of the patient, hardness, swelling, and sensitivity were found in the left testis.…”

“…Embryonal carcinoma is a non-seminomatous germ cell tumor and seen in only 1-5% [1][2][3][4][5][6][7][8]. In general, following the seminoma, it constitutes the second-most frequently (80%) seen tumor component of mixed germ cell tumors [2].…”

“…For this reason, early diagnosis and treatment of embryonal carcinoma cases are very important [3]. As in many testicular tumors, embryonal carcinoma is also detected by the patient or coincidentally in examination in form of pain-free or (less frequently) painful palpable mass [5][6][7][8][9][10]. When pain or mass is detected in testis, the first imaging method to be used is USG.…”