Primary epithelioid angiosarcoma of the thyroid: A case report

Abstract

Angiosarcoma of the thyroid is a rare and aggressive primary malignant tumour of the thyroid. We report the case of a 69‐year‐old woman who presented with a red and sore skin area at the right‐anterior region of the neck. Ultrasound examination and computed tomography scan showed a non‐homogeneous mass in the right thyroid lobe. Fine needle aspiration cytology was suggestive of atypical vascular proliferation and so the patient underwent right thyroid lobectomy. The specimen measured 6 × 5 × 2.5 cm, and a reddish nodule was found, including a whitish central area of maximum 4 cm in diameter. Immunohistochemistry showed CD31 and ERG positivity, while thyroglobulin, calcitonin and TTF‐1 expression were negative, indicating a diagnosis of angiosarcoma.

A case of angiosarcoma metastasis to pleural effusion

“…In one report, 4 angiosarcoma cells showed spindle cell morphology on fine needle aspiration cytology (FNAC). In another case, 5 round or oval cells similar to those in our case were reported. These cells from FNA specimens often have rich cytoplasm and obvious nucleoli, and pathological mitosis is easy to observe.…”

Neck Surgery for Non-Well Differentiated Thyroid Malignancies: Variations in Strategy According to Histopathology

“…Clinical and radiological features are nonspecific. These tumors are highly aggressive malignant vascular tumors, characterized by a severe local course and rapid metastatic dissemination and are associated with a dismal prognosis [80,[91][92][93]. Most of these tumors appear as painless, poorly encapsulated, infiltrative masses and patients present with compression symptoms including a lesion on the neck, dyspnea, hoarseness, and dysphagia due to the rapid growth.…”