Primary extraoral sclerosing microcystic adenocarcinoma of the salivary gland

Magnetic resonance imaging findings of sclerosing microcystic adenocarcinoma: A case report and review of the literature

“… [16] 73 M Left parotid gland Not stated Excision Disease free (4) 20 Elizabath et al. [17] 67 F Right parotid gland MRI Excision and adjuvant radiotherapy Disease free (6) 21 Lee et al. [18] 48 M Tongue FDG-PET/CT Excision Disease free (30) 22 Present case 61 F Floor of mouth MRI Excision and adjuvant radiotherapy Disease free (21) …”

“…To our knowledge, no study has conducted a detailed review of the MRI findings of SMA. Among the 21 reported cases of SMA, imaging findings were described in 4, as follows: computed tomography (CT) (n = 2), 18F-fluorodeoxyglucose-positron emission tomography/CT (18F-FDG-PET/CT) (n = 1), and MRI (n = 2) [ 11 , 13 , 17 , 18 ]. As these reports did not describe the imaging findings of the SMA in detail, we reviewed the available images and summarized the findings as follows.…”

“…The lesion showed high uptake of FDG on 18F-FDG-PET/CT (standardized uptake value not stated) [18] . MRI findings revealed an iso-signal intensity to muscle on T2WI with gadolinium enhancement [ 11 , 17 ]. Consistent with the findings of previous studies, the lesions, in this case, were visualized as partially ill-defined masses with iso to slightly higher signal intensity than the surrounding muscle on T2WI and uniform gadolinium enhancement.…”

“…proposed the term “sclerosing microcystic adenocarcinoma (SMA)” for a rare malignant tumor occurring in the salivary glands, closely resembling cutaneous MAC [11] . To our knowledge, 21 cases of SMA have been reported, but none have evaluated the magnetic resonance imaging (MRI) findings of SMA in detail [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] . Here, we report an additional case of SMA of the floor of the mouth and discuss its MRI findings.…”