Primary follicular lymphoma of the conjunctiva in a 6-year-old child

Malignant lymphoma of the conjunctiva

“…Only 9% of the EMZL patients experienced progression or recurrence during a 1-year follow-up period, and even fewer in FL cases. 48,117,133 In addition, there were no progressions or recurrences among the indolent conjunctival plasmacytomas. 64,112 The low progression or recurrence rates also appear to apply to the high-grade DLBCLs, whereas conjunctival MCL carries a somewhat worse prognosis, with around 15% of patients having progression or recurrence during a 1-year follow-up period.…”

“…15,85,94 Similar findings apply to FL, which is likewise mainly found in the bulbar and forniceal conjunctiva. 1,48 Because of the sparse number of cases of the remaining types of lymphoma, there are no clear tendencies regarding their location.…”

“…This alternative has mainly been used in the management of the low-grade lymphomas, especially when they present as encapsulated lesions. 16,19,48 Because of tumor microinfiltration into the surrounding tissue, however, the risk of recurrence is high if no other treatment is administered, with approximately every third patient having progression or recurrence during a 3-year follow-up period. 8,19…”

A Case of Conjunctival Follicular Lymphoma Mimicking Mucosa-Associated Lymphoid Tissue Lymphoma

“…8 To the best of our knowledge, there are only a few reports of primary conjunctival follicular lymphoma in the literature on both children and adults. 1,12,15 The differentiation of follicular lymphoma from other variants is important because these lymphomas exhibit different clinical behaviors and outcomes. 2 The early clinical picture and age of presentation may overlap with a simple case of dry eye irritation.…”

Uncommon non‐Hodgkin lymphomas of childhood: pathological diagnosis, clinical features and treatment approaches

“…Most paediatric FLs are successfully managed with conservative therapeutic approaches (Lorsbach et al , ; Gaffar et al , ; Oschlies et al , ; Kumar et al , ; Perkins & Gross, ; Yang et al , ; Lones et al , ; Attarbaschi et al , ). In the study by Lorsbach et al (), multiagent chemotherapy (CHOP: cyclophosphamide, doxorubicin, vincristine, prednisolone) was used in most cases with limited ( n = 4) use of involved field irradiation.…”