Primary follicular mucinosis: excellent response to treatment with photodynamic therapy

Abstract

References1 Michaëlsson G, Gustafsson K, Hagforsen E. The psoriasis variant palmoplantar pustulosis can be improved after cessation of smoking. J Am Acad Dermatol 2006; 54: 737 -738. 2 Fortes C, Mastoeni S, Leffondré K et al. Relationship between smoking and the clinical severity of psoriasis. Arch Dermatol 2005; 141: 1580 -1584. 3 Herron M, Hinckley M, Hoffman M et al. Impact of obesity and smoking on psoriasis presentation and management.

Follicular Mucinosis Associated With Nonlymphoid Skin Conditions

“…24 Recently, hydroxychloroquine (HCQ) 25,26 have also been used with success. Few reports have informed that some patients had been effectively treated with isotretinoin 23 and photodynamic therapy.…”

A case of idiopathic follicular mucinosis treated with bexarotene gel

“…Common treatments include topical, intralesional, and systemic corticosteroids. In addition, topical and systemic psoralen plus ultraviolet A light (PUVA) therapy, topical nitrogen mustard, and radiation therapy have demonstrated some success . Isolated cases document the beneficial responses of pimecrolimus, dapsone, indomethacin, minocycline, isotretinoin, hydroxychloroquine, and interferons …”

Treatment of so-called idiopathic follicular mucinosis with hydroxychloroquine

“…[7][8][9] More recent publications indicated a chronic course with recurrent or persistent lesions in the majority of patients. 3 Many anecdotal therapies, such as topical, intralesional and systemic steroids, topical retinoids, systemic isotretinoin, dapsone, interferon, cyclophosphamide, methotrexate, psoralen plus ultraviolet A, antihistamines, minocycline, superficial radiation, X-rays, photodynamic therapy and pimecrolimus, have been used for the empirical treatment 3,[10][11][12] No treatment is consistently effective or confirmed in a larger population of patients. Hence, there exists no first-line therapy for FM.…”