Primary gallbladder lymphoma presenting as a polyp

Abstract

SUMMARYWe present an unusual case of a 75-year-old woman, with no significant medical history, presenting with ongoing weight loss and change in bowel habit. Her physical examination and initial blood tests were all normal, and, therefore, radiographic imaging was undertaken. Ultrasound and CT of the abdomen confirmed a gallbladder polyp and a laparoscopic cholecystectomy was subsequently performed. Histological analysis confirmed primary gallbladder lymphoma. This case report is the first to present gallbladder lymphoma presenting as a polyp. The authors discuss the incidence, presentation and management of gallbladder lymphoma. BACKGROUND

Diffuse large B-cell lymphoma of the gallbladder arised 8 years after malignant lymphoma of the right testis: A case report and literature review

“…The histological types were frequently reported as mucosa-associated lymphoid tissue (MALT) lymphoma [ 9 , 10 ], DLBCL [ 7 , 11 ], IVLBCL [ 6 , 12 ] and follicular lymphoma [ 13 , 14 ], and there were rare cases with the coexistence of DLBCL and MALT lymphoma [ 15 ], and malignant lymphoma and gallbladder adenocarcinoma [ 16 ]. We compare the clinical features of reported cases of gallbladder MALT lymphoma (n = 13) and gallbladder DLBCL (n = 15) in Table 2 to evaluate the difference in characteristics between the two subtypes, which are considered to be common in gastrointestinal malignant lymphoma, including the stomach.…”

Gallbladder lymphoma detected by 18F-fluorodeoxyglucose positron emission tomography

“…Gallbladder involvement is rare, and it has only been reported on several occasions in the literature, mostly published in the pre PET era. [ 1 2 3 4 5 6 ] Previously, the staging of lymphoma was heavily dependent on CT, which had only limited sensitivity. The shift to PET/CT staging for lymphoma has increased the sensitivity for disease detection in both nodal and extranodal sites, including the gallbladder.…”

“…Very rarely, the gallbladder becomes involved as a primary site or as part of widespread disease. [ 1 2 3 4 5 6 ] We report a case of large B-cell lymphoma in the gallbladder in 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography (PET)/computed tomography (CT).…”

Imaging diagnosis of gallbladder adenoma

“…Gallbladder adenoma itself exhibited no clinical symptoms, and the symptoms were mainly induced by cholecystitis, cholelith disease. About 1/3 to 3/5 of the gallbladder adenoma was accompanying with gallbladder stone [11][12][13]. The form of gallbladder adenoma was larger, multiple, and can cause a series of clinical symptoms [14].…”