Primary Gastric Squamous Cell Carcinoma Presenting as a Huge Subepithelial Tumor: A Case Report

Abstract

Primary gastric squamous cell carcinoma is a very rare cancer whose mechanism has not been clearly elucidated. To date, less than 100 cases have been reported. However, only one case was reported to be presented as a subepithelial tumor. A 69-year-old woman complained of melena, dizziness for one month, and anorexia for two months. Esophagogastroduodenoscopy revealed a large bleeding subepithelial tumor in the upper body of the stomach. Endoscopic biopsy diagnosed with gastric squamous cell carcinoma. In abdominal computed tomography (CT), large, poorly heterogeneous enhancing, intraluminal protruding masses were observed in the upper body of the stomach, and several regional lymph node enlargements were seen around the stomach. There were no other abnormal findings or metastasis in chest CT and bone scan. The patient is being followed up because of refusing any further treatment after endoscopic hemostasis.