Primary Gastric Synovial Sarcoma in a Child: A Case Report and Review of the Literature

Abstract

Synovial sarcoma is a mesenchymal neoplasm that shows a specific t(X;18) translocation that leads to the formation of SS18-SSX gene fusions and is most commonly seen in soft tissues of the extremity. The gastrointestinal tract is a very rare site of involvement. We report a case of primary gastric synovial sarcoma in a 13-year-old male child. Synovial sarcoma should be included in the differential diagnosis when spindle cell neoplasms are encountered in the stomach. A high degree of suspicion, followed by the necessary immunohistochemistry and molecular studies, is required to make an accurate diagnosis.

Primary gastric synovial sarcoma resected by laparoscopic endoscopic cooperative surgery of the stomach: a case report

“…Tumors were often locally located in the body and fundus of the stomach, with a median size of 5.46 cm; many also had ulcers. Recently, reports of this tumor type have been increasing [24,[27][28][29][30], which may be a result of improved understanding of this tumor type and advances in diagnostic ability.…”

“…A total of 44 cases of primary gastric synovial sarcoma have been reported thus far, and surgical procedures conducted were as follows: tumorectomy in five cases, wedge resection in nine cases, partial gastrectomy in seven cases, gastrectomy in four cases, distal gastrectomy in two cases, total gastrectomy in three cases, antrectomy in one case, intragastric resection in one case, and surgical resection in two cases. No data were available in ten cases [24,[26][27][28][29][30]. Thus, LECS procedure has not been reported.…”

“…Recently, reports of this tumor type have been increasing [ 24 , 27 – 30 ], which may be a result of improved understanding of this tumor type and advances in diagnostic ability.…”