Primary Gastric Tuberculosis Mimicking Gastrointestinal Stromal Tumor

Gupta, Vishal; Goel, Madhu Mati; Medappil, Noushif; Rai, Praveer; Gupta, Parul; Chandra, Abhijit

doi:10.1038/ajg.2012.120

Cited by 15 publications

(15 citation statements)

References 7 publications

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“…The most common site of gastric TB is the antrum region, especially the lesser curvature near the prepyloric region [3][4][5][6]15]. Additionally, this is the most common site for peptic ulcers, thus resulting in a mucosal breach at this site.…”

Section: Discussionmentioning

confidence: 99%

“…Clinically, gastric tuberculosis often resembles peptic ulcer disease, cancer or lymphoma under endoscopy [1,2]. There have been several reported cases of gastric TB mimicking a subepithelial tumor or gastrointestinal stromal tumor, but most cases were mainly located in the antrum of the stomach [3][4][5][6]. Gastric tuberculosis in the cardia of the stomach usually appears like a gastric stromal tumor [4].…”

Section: Introductionmentioning

confidence: 99%

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Primary isolated asymptomatic gastric tuberculosis of the cardia mimicking gastric stromal tumor: a rare case report and literature review

Lv¹,

Tang²,

Meng³

et al. 2020

BMC Gastroenterol

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Background: Primary isolated gastric TB of the cardia presenting as a submucosal tumor is extremely rare. Case presentation: A 60-year-old female was admitted to our department; endoscopy revealed a smooth protruding lesion in the gastric cardia. The patient was diagnosed with a gastric cardia stromal tumor and the lesion was seen in muscularis propria by endoscopic ultrasonography (EUS). Endoscopic submucosal dissection (ESD) revealed that the lesion was filled with a milky, white liquid and white granulation tissue. Acid-fast specimen staining was negative. Hematoxylin and eosin staining showed patches of caseating necrosis and granulomatous inflammation. Gene sequencing subsequent to polymerase chain reaction (PCR) analysis of the ESD specimen identified Mycobacterium tuberculosis (M. TB) DNA fragments. The patient was put on ATT for 6 months. Conclusion: Primary isolated gastric TB of the cardia should be suspected in patients without clinical symptoms whose manifestations are similar to those associated with submucosal tumors. TB-PCR may be helpful for further diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Primary isolated asymptomatic gastric tuberculosis of the cardia mimicking gastric stromal tumor: a rare case report and literature review

Lv¹,

Tang²,

Meng³

et al. 2020

BMC Gastroenterol

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“…Finding of an abscess is very unusual among gastric TB cases described in the literature. Only a few reports of submucosal lesions have been published where exudative material and granulomatous inflammation were found [ 10 , 11 ]. Other cases have previously been reported as solid gastric masses without abscess formation and the diagnosis has been made based on microscopic tissue examination or PCR [ 12 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

Tuberculous Gastric Abscess in a Patient with AIDS: A Rare Presentation

Nayyar

Torres

Malvestutto

2016

Case Reports in Infectious Diseases

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Tuberculosis is a healthcare concern that affects millions of individuals around the globe. Coinfection with HIV has changed both the clinical presentation and the outcome of the disease dramatically in the last few decades. Extrapulmonary tuberculosis is seen more frequently in the immunocompromised host. An unusual case of gastric tuberculosis in an AIDS patient is reported here. A 49-year-old female with AIDS was admitted for fever and epigastric pain. A gastric submucosal abscess was observed on imaging and confirmed by biopsy showing numerous neutrophils and acid-fast bacilli. Aspirate grew Mycobacterium tuberculosis. This report highlights a very unusual presentation of tuberculosis in an immunodeficient patient. High clinical suspicion for opportunistic infections in unusual locations should be maintained in these patients presenting with clinical syndromes that do not respond to standard treatments. New diagnostic modalities facilitate accurate identification of these infections.

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“…[8,9] A submucosal bulge with normal overlying mucosa has been rarely reported with tuberculosis. [6,7] Isolated gastric tuberculosis is very rare with antrum being the most common site of involvement, and its endoscopic appearances are variable with both ulcers and polypoidal lesions being described. [10] The rarity of gastric involvement is due to the bactericidal nature of the gastric acid, rapid emptying of the stomach, local immunity of gastric wall and the paucity of lymphoid tissue in the gastric wall.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5] A submucosal bulge with the normal overlying mucosa is usually due to submucosal tumors or vascular lesions and has been rarely reported with tuberculosis. [5][6][7][8] We present a 28-year-old female, who had gastric tuberculosis and the lesion on endoscopy mimicked a submucosal tumor.…”

Section: Introductionmentioning

confidence: 97%

Primary gastric tuberculosis mimicking a submucosal tumor

Sharma

Gunjan

Chhabra

et al. 2015

Journal of Digestive Endoscopy

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Gastric tuberculosis is very rare and is usually associated with pulmonary tuberculosis. Endoscopically, it usually resembles peptic ulcer disease or malignancy. We present a 28-year-old female who had a submucosal lesion in the body of the stomach that mimicked a submucosal tumor. Endoscopic ultrasound guided fine needle aspiration yielded caseous material, and the cytological examination confirmed the diagnosis of tuberculosis.

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Primary Gastric Tuberculosis Mimicking Gastrointestinal Stromal Tumor

Cited by 15 publications

References 7 publications

Primary isolated asymptomatic gastric tuberculosis of the cardia mimicking gastric stromal tumor: a rare case report and literature review

Primary isolated asymptomatic gastric tuberculosis of the cardia mimicking gastric stromal tumor: a rare case report and literature review

Tuberculous Gastric Abscess in a Patient with AIDS: A Rare Presentation

Primary gastric tuberculosis mimicking a submucosal tumor

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