Primary germ cell tumor of the diaphragm

Approach to diagnosis and treatment of pediatric primary tumors of the diaphragm

“…Including our series, 41 of these tumors have been found in patients 18 years of age or less [1][2][3][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22]. In reviewing this cohort of patients, there is an equal incidence of PDT in boys and girls, they are found with equal frequency on the right and on the left, and most (n = 32, 78%) are malignant.…”

Persisting Cough as the Single Presenting Symptom of an Intrathoracic Tumor in a Nine-Month-Old Child with Adenovirus Airway Infection

“…The remaining locations (24%) are in the mediastinum, the retroperitoneum and other midline structures [5][6][7]. Teratomas arising within the chest have been described to be located in the anterior or posterior mediastinum in the vicinity of the aorta, esophagus, pericardium, lung and diaphragm [5,7,8]. Other tumor entities such as manifestations of lymphomas, neuroblastomas, sarcomas or other kinds of small round blue cell tumors and metastases have to be excluded, as well as nonmalignant causes which mimicry a tumor as an infectious manifestation.…”

Retropleural teratoma presenting as an abdominal mass in a 9-month-old boy

“…Typically, they arise from the anterior mediastinum (thymus) and can become quite large, potentially leading to cardiopulmonary compromise. Less frequently, thoracic teratomas may arise from the posterior mediastinum, aorta, esophagus, pericardium, lung, and diaphragm [4][5][6][7][8][9][10]. The lateral chest cavity, including the costovertebral sulcus and the costophrenic sulcus, is even more rare a location to arise [11].…”