Primary hepatic carcinoid tumor in children

Diagnostic problem of Primary Hepatic Neuroendocrine Tumor in 18-year-old woman: A case report

“…Neuroendocrine Tumor arises primarily in the gastrointestinal tract and bronchus. The appendix is the most common site of NET [9] . Meanwhile, Primary Hepatic Neuroendocrine Tumor is a rare case, and it's quite challenging to diagnose and treat.…”

“…Most PHNET cases were occurred in adults above fifty years old [5] . Only a few patients were diagnosed when they are less than eighteen years old [9] . According to Pastrian et al, the size of a giant PHNET is more than 8 cm.…”

“…The Neuroendocrine Tumor can synthesize and release vasoactive amines and regulatory peptides such as serotonin, bradykinin, substance P, prostaglandins E and F, dopamine, and histamine. The increase of serotonin and bradykinin can cause flushing and diarrhea in Neuroendocrine Tumor patients [9] . But it was not found in our patient, so it was unlikely that the liver mass was diagnosed with Neuroendocrine Tumor at first.…”

Neuroendocrine Tumors of the Hepatobiliary Tract

“…Notwithstanding the rarity of primary hepatic carcinoid, numerous reports have described lesions that were classified or interpreted as primary well-differentiated hepatic neuroendocrine tumors or, in most publications, as carcinoid tumors. Few cases have been reported in the pediatric age group (Foley et al 2008).…”