Primary hyperparathyroidism caused by a parathyroid carcinoma in a 16-year-old male neutered cat with concurrent chronic kidney disease

Faucher, Mathieu R; Freiche, Valérie; Bongrand, Yannick; German, Alexander J.

doi:10.1080/01652176.2014.900876

Cited by 5 publications

(10 citation statements)

References 15 publications

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Section: Discussioncontrasting

confidence: 75%

“…Furthermore, no cervical mass was palpable in our cat. In contrast to reported clinical examination findings of other hyperparathyroid cats in which a palpable cervical mass was found, 5,15,16 this is uncommon in dogs. 17 Side effects of chemical ablation in the cat were limited to a slight change of voice for 6 weeks and a mild prolapse of the nictitating membrane until 10 weeks after chemical ablation.…”

Section: Discussionmentioning

confidence: 56%

Section: Discussionmentioning

confidence: 99%

“…iCa concentration normalised within 24 days after surgery and no supplementation was given. 16 Differentiation between an adenoma and carcinoma was not possible based on the cytological samples. This is not surprising as even histologically, differentiation between benign and malignant parathyroid masses is difficult.…”

Section: Discussionmentioning

confidence: 99%

“…14 In contrast to this, and similar to the case reported here, Faucher et al reported a PTH concentration of 868 pg/ml (RI <40 pg/ml) in a hyperparathyroid cat with a parathyroid carcinoma. 16 Whenever data are available, the decline of PTH concentration after treatment is prompt. Parathyroidectomy in dogs resulted in a median decline of 84.9% of PTH 10 mins post-procedure.…”

Section: Discussionmentioning

confidence: 99%

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Percutaneous ultrasound-guided ethanol ablation for treatment of primary hyperparathyroidism in a cat

Riehl¹,

Hartmann²,

Rohrberg³

et al. 2019

Journal of Feline Medicine and Surgery Open Reports

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Case summary A 9-year-old male neutered European Shorthair cat was presented owing to vomiting and mild weight loss. Clinical examination was normal, but biochemistry results showed increased concentrations of total calcium (4.05 mmol/l; reference interval [RI] 2.20–2.90 mmol/l) and ionised calcium (iCa) (2.19 mmol/l; RI 1.12–1.40 mmol/l), as well as hypophosphataemia (2.5 mg/dl; RI 3.1–7.5 mg/dl). Parathyroid hormone (PTH) concentration (>1000 pg/ml) was markedly increased, while parathyroid hormone-related protein concentration (<0.8 pmol/l) was normal. Neck ultrasound showed a large left parathyroid mass (13 × 7 × 6 mm). Under general anaesthesia and with ultrasonographic guidance, a fine-needle aspiration of the mass followed by chemical ablation with 2 ml 96% ethanol was performed. The cat was re-evaluated and iCa concentration measured 24 h, 72 h, 5 days, 4 weeks and 4 months post-ablation. Normocalcaemia was reached within 24 h, remained stable throughout the whole evaluation period and the concentration of PTH normalised 4 months later. Vomiting stopped promptly after chemical ablation and a slight change in voice, as well as a mild prolapse of the nictitating membrane, were the only side effects after the treatment but resolved some weeks later. Relevance and novel information To our knowledge, this is the first report of successful chemical ablation of a parathyroid mass in a cat with primary hyperparathyroidism. Chemical ablation might therefore be a possible alternative to parathyroidectomy in cats.

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Section: Discussioncontrasting

confidence: 75%