Primary Hypothyroidism and Concomitant Bilateral Ovarian Masses

Fernández‐Real, José‐Manuel; Ricart-Engel, Wifredo; Maroto-Genover, A.; Macia, F.

doi:10.1515/jpem.1995.8.4.263

Cited by 5 publications

(1 citation statement)

References 10 publications

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“…The diagnostic criteria of PCOS at the Reproductive Endocrine Committee of the Japan Society of Obstetrics and Gynecology list the following as essential requirements: 1) irregular menstruation, 2) high level of basal LH secretion, and 3) ultrasonographic demonstration of multiple cystic changes of ovary (4). On the other hand, it has been reported that high circulating TSHlevel associated with hypothyroidism causes ovarian enlargement with cyst formation, which presents PCOS-like features (5)(6)(7)(8)(9). Here, we report 4 case of hypothyroidism complicated by polycystic ovary and pituitary enlargement with hypothyroidism, which is a commonthyroid disease amongadult females.…”

Section: Introductionmentioning

confidence: 78%

Regression of Both Pituitary and Ovarian Cysts after Administration of Thyroid Hormone in a Case of Primary Hypothyroidism.

et al. 2001

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We report a 19-year-old woman who was diagnosed as polycystic ovary. Hypothyroidism with a markedly elevated TSHlevel and an enlarged pituitary gland on MRI were noted. The 123I uptake was decreased to 6.5%. After treatment with thyroid hormone, regression of the enlarged pituitary and the ovarian cysts was observed. In the present case, hypothyroidism was considered to have caused a reversible enlargement of the pituitary gland and concomitant polycystic ovary. Weconcluded that the polycystic ovary might have resulted from the effects of an excessive amount of TSHon immature ovaries. (Internal Medicine 40: 751-755, 2001)

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Section: Introductionmentioning

confidence: 78%

Regression of Both Pituitary and Ovarian Cysts after Administration of Thyroid Hormone in a Case of Primary Hypothyroidism.

et al. 2001

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Pituitary hyperplasia in childhood primary hypothyroidism: a review

Sapkota¹,

Karn²,

Sapkota

2021

Childs Nerv Syst

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Multiple Ovarian Cysts in a Young Girl with Severe Hypothyroidism

Panico

Lupoli

Fonderico

et al. 2007

Thyroid

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Case study of a young female patient with severe hypothyroidism due to autoimmune thyroiditis and multiple ovarian cysts is reported. A 14-year 7-month-old girl presented with pelvic and abdominal pain and severe asthenia. Her last menstrual period was 10 months before presentation. Physical examination showed obesity; apathetic and flat expression; periorbital puffiness; pale, cold, dry skin and slow sustained reflexes; swelling in the hands and feet; no galactorrhea; a hardly palpable thyroid gland; and ovaries with a palpable irregular surface. Her heart rate was 90 bpm with a blood pressure within the normal range (110/70 mmHg). Laboratory findings showed severe hypothyroidism (thyroid-stimulating hormone [TSH]: 960 mIU/L), gravis macrocytic anemia, hyperfibrinogenemia, and hyperprolactinemia. Imaging examinations revealed a normal-size thyroid with irregular echogenicity, strongly hypoechogenous area at the neck ultrasonography, bilateral multilocular ovarian masses with cystic components at pelvic ultrasound and computed tomography, and both anterior and posterior pericardial effusion at echocardiography. As soon as thyroid replacement therapy was initiated, all symptoms progressively disappeared and biochemical and hormonal values normalized, while the right ovary did not decrease in size during the follow-up period. For this reason, our patient underwent right ovarian wedge resection 14 months after the initiation of medication replacement. Ovarian histological examination showed a benign ovarian cyst with extensive hemorrhage and myxedematous infiltration. It is concluded that it is important to recognize early in young girls the association between large multiple ovarian cysts and high elevated levels of TSH in order to resolve this disorder with substitutive therapy.

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Primary Hypothyroidism and Concomitant Bilateral Ovarian Masses

Cited by 5 publications

References 10 publications

Regression of Both Pituitary and Ovarian Cysts after Administration of Thyroid Hormone in a Case of Primary Hypothyroidism.

Regression of Both Pituitary and Ovarian Cysts after Administration of Thyroid Hormone in a Case of Primary Hypothyroidism.

Pituitary hyperplasia in childhood primary hypothyroidism: a review

Multiple Ovarian Cysts in a Young Girl with Severe Hypothyroidism

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